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Correction for Residual Effects of B1+ Inhomogeniety on MT Saturation in FLASH-Based Multi-Parameter Mapping of the Brain

Helms, Gunther LU orcid (2015) ISMRM 23rd Annual Meeting and Exhibition In Proceedings of the ISMRM 23. p.3360-3360
Abstract
Maps of the MT-saturation as derived in FLASH-based multi-parameter mapping (MPM) are largely corrected for effects of flip angle inhomogeneity. Here, we present a heuristic model for residual effects of B1+ that is rooted in the dynamics of macromolecule saturation. Model parameters were validated for brain tissues by variation of the MT-pulse flip angle in an established MPM protocol. White and gray matter exhibited similar values. A post-hoc correction by an independent B1+ map yielded more symmetric MT maps and reduced variation across white matter.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Proceedings of the International Society for Magnetic Resonance in Medicine Annual Meeting 2015
series title
Proceedings of the ISMRM
volume
23
article number
3360
pages
1 pages
publisher
International Society for Magnetic Resonance in Medicine
conference name
ISMRM 23rd Annual Meeting and Exhibition
conference location
Toronto, Canada
conference dates
2015-05-30 - 2015-06-05
ISSN
1545-4428
project
Multiparametric mapping of the brain at 7T using gradient echoes
language
English
LU publication?
yes
id
5331f16b-5b38-4880-a3c8-e2928a56fc89
alternative location
https://index.mirasmart.com/ISMRM2015/PDFfiles/3360.pdf
date added to LUP
2019-06-12 12:28:40
date last changed
2020-08-03 02:17:36
@inproceedings{5331f16b-5b38-4880-a3c8-e2928a56fc89,
  abstract     = {{Maps of the MT-saturation as derived in FLASH-based multi-parameter mapping (MPM) are largely corrected for effects of flip angle inhomogeneity. Here, we present a heuristic model for residual effects of B1+ that is rooted in the dynamics of macromolecule saturation. Model parameters were validated for brain tissues by variation of the MT-pulse flip angle in an established MPM protocol. White and gray matter exhibited similar values. A post-hoc correction by an independent B1+ map yielded more symmetric MT maps and reduced variation across white matter.<br/><br/>}},
  author       = {{Helms, Gunther}},
  booktitle    = {{Proceedings of the International Society for Magnetic Resonance in Medicine Annual Meeting 2015}},
  issn         = {{1545-4428}},
  language     = {{eng}},
  month        = {{05}},
  pages        = {{3360--3360}},
  publisher    = {{International Society for Magnetic Resonance in Medicine}},
  series       = {{Proceedings of the ISMRM}},
  title        = {{Correction for Residual Effects of B1+ Inhomogeniety on MT Saturation in FLASH-Based Multi-Parameter Mapping of the Brain}},
  url          = {{https://lup.lub.lu.se/search/files/65881487/Helms_ProceedingsISMRM_23_2015_3360.pdf}},
  volume       = {{23}},
  year         = {{2015}},
}