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Role of CD8-positive cells in radioimmunotherapy utilizing (177)Lu-mAbs in an immunocompetent rat colon carcinoma model.

Elgström, Erika LU ; Eriksson, Sophie LU ; Ohlsson, Tomas G LU ; Nilsson, Rune LU and Tennvall, Jan LU (2015) In EJNMMI Research 5.
Abstract
CD8-positive cells might play a crucial role in the therapeutic response to radiation, which has however not been investigated in radioimmunotherapy (RIT). The aim of this study was to evaluate whether cytotoxic T cells affect the response of established tumors and, above all, if they delay or prevent the development of distant metastases after RIT, using an immunocompetent syngeneic rat colon carcinoma model.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
EJNMMI Research
volume
5
publisher
BioMed Central
external identifiers
  • pmid:25853009
  • wos:000358126600001
  • scopus:84923803980
ISSN
2191-219X
DOI
10.1186/s13550-014-0079-6
language
English
LU publication?
yes
id
ad6387e6-5519-4ae0-ac1c-705b53bc0346 (old id 5345156)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25853009?dopt=Abstract
date added to LUP
2015-05-06 14:53:55
date last changed
2017-01-01 06:25:30
@article{ad6387e6-5519-4ae0-ac1c-705b53bc0346,
  abstract     = {CD8-positive cells might play a crucial role in the therapeutic response to radiation, which has however not been investigated in radioimmunotherapy (RIT). The aim of this study was to evaluate whether cytotoxic T cells affect the response of established tumors and, above all, if they delay or prevent the development of distant metastases after RIT, using an immunocompetent syngeneic rat colon carcinoma model.},
  articleno    = {3},
  author       = {Elgström, Erika and Eriksson, Sophie and Ohlsson, Tomas G and Nilsson, Rune and Tennvall, Jan},
  issn         = {2191-219X},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {EJNMMI Research},
  title        = {Role of CD8-positive cells in radioimmunotherapy utilizing (177)Lu-mAbs in an immunocompetent rat colon carcinoma model.},
  url          = {http://dx.doi.org/10.1186/s13550-014-0079-6},
  volume       = {5},
  year         = {2015},
}