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Synthetic Strategies in Molecular Imprinting.

Ye, Lei LU (2015) In Advances in Biochemical Engineering, Biotechnology 150(Online 04 April 2015). p.1-24
Abstract
: This chapter introduces the basic principle and the synthetic aspects of molecular imprinting. First, the use of a molecular template to guide the location of functional groups inside molecularly imprinted cavities is explained. Three different mechanisms that ensure a molecular template associates with functional monomers or the imprinted polymers, that is, through reversible covalent, noncovalent, and sacrificial covalent bonds, are then described. The main focus is put on noncovalent molecular imprinting using free radical polymerization. The merits of using classical radical polymerization and more sophisticated, controlled radical polymerization are analyzed. After these synthetic chemistry aspects, the chapter continues to discuss... (More)
: This chapter introduces the basic principle and the synthetic aspects of molecular imprinting. First, the use of a molecular template to guide the location of functional groups inside molecularly imprinted cavities is explained. Three different mechanisms that ensure a molecular template associates with functional monomers or the imprinted polymers, that is, through reversible covalent, noncovalent, and sacrificial covalent bonds, are then described. The main focus is put on noncovalent molecular imprinting using free radical polymerization. The merits of using classical radical polymerization and more sophisticated, controlled radical polymerization are analyzed. After these synthetic chemistry aspects, the chapter continues to discuss the different polymerization processes that can be used to prepare well-defined polymer monoliths, microspheres, and nanoparticles. New top-down processing techniques that produce micro- and nanopatterns of imprinted polymers are also reviewed. The chapter finishes with a brief introduction to using imprinted polymers as building blocks to construct new functional materials and devices, which we consider as one important direction for further development. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Advances in Biochemical Engineering, Biotechnology
volume
150
issue
Online 04 April 2015
pages
1 - 24
publisher
Springer
external identifiers
  • pmid:25840705
  • wos:000365222300002
  • scopus:84938085711
ISSN
0724-6145
DOI
10.1007/10_2015_313
language
English
LU publication?
yes
id
9598d9eb-bbbb-40aa-bed9-d9e7067eb20e (old id 5345574)
date added to LUP
2015-04-30 10:14:34
date last changed
2017-11-05 04:01:40
@article{9598d9eb-bbbb-40aa-bed9-d9e7067eb20e,
  abstract     = {: This chapter introduces the basic principle and the synthetic aspects of molecular imprinting. First, the use of a molecular template to guide the location of functional groups inside molecularly imprinted cavities is explained. Three different mechanisms that ensure a molecular template associates with functional monomers or the imprinted polymers, that is, through reversible covalent, noncovalent, and sacrificial covalent bonds, are then described. The main focus is put on noncovalent molecular imprinting using free radical polymerization. The merits of using classical radical polymerization and more sophisticated, controlled radical polymerization are analyzed. After these synthetic chemistry aspects, the chapter continues to discuss the different polymerization processes that can be used to prepare well-defined polymer monoliths, microspheres, and nanoparticles. New top-down processing techniques that produce micro- and nanopatterns of imprinted polymers are also reviewed. The chapter finishes with a brief introduction to using imprinted polymers as building blocks to construct new functional materials and devices, which we consider as one important direction for further development.},
  author       = {Ye, Lei},
  issn         = {0724-6145},
  language     = {eng},
  number       = {Online 04 April 2015},
  pages        = {1--24},
  publisher    = {Springer},
  series       = {Advances in Biochemical Engineering, Biotechnology},
  title        = {Synthetic Strategies in Molecular Imprinting.},
  url          = {http://dx.doi.org/10.1007/10_2015_313},
  volume       = {150},
  year         = {2015},
}