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Improved Wall Shear Rate Method for Robust Measurements

Ricci, S.; Swillens, A.; Ramalli, A.; Cinthio, Magnus LU ; Segers, P. and Tortoli, P. (2014) IEEE International Ultrasonics Symposium (IUS), 2014 In 2014 IEEE International Ultrasonics Symposium (IUS) p.432-435
Abstract
The Wall Shear Rate (WSR) represents an important parameter correlated with cardiovascular diseases, like, for example the atherosclerotic plaque formation. The WSR can be obtained as the radial blood velocity gradient assessed in the wall proximity. The WSR is typically approximated by using flow models like Poiseuille and/or Womersley applied to the measured center-line velocity. However these models cannot account for the complex flow configurations generated by the real geometry of the vessel, and the WSR estimate is inaccurate. The direct measurement of the velocity gradient through a Doppler high-resolution multigate technique can achieve a better accuracy, but the signal near the wall is affected by clutter. In this work an improved... (More)
The Wall Shear Rate (WSR) represents an important parameter correlated with cardiovascular diseases, like, for example the atherosclerotic plaque formation. The WSR can be obtained as the radial blood velocity gradient assessed in the wall proximity. The WSR is typically approximated by using flow models like Poiseuille and/or Womersley applied to the measured center-line velocity. However these models cannot account for the complex flow configurations generated by the real geometry of the vessel, and the WSR estimate is inaccurate. The direct measurement of the velocity gradient through a Doppler high-resolution multigate technique can achieve a better accuracy, but the signal near the wall is affected by clutter. In this work an improved velocity reconstruction method for WSR measurement is proposed. It is based on the measurement of the actual velocity profile and a two-step interpolation that reconstructs the velocity in the wall proximity. The method, verified through realistic multiphysics simulations of a carotid artery, achieves a 5% RMS error for velocity reconstruction and a -10.5% underestimation in WSR assessment. The method was also tested on 14 healthy volunteers. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Wall Shear Rate, Multiphysics Simulations, Blood Velocity Profile
in
2014 IEEE International Ultrasonics Symposium (IUS)
pages
432 - 435
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
conference name
IEEE International Ultrasonics Symposium (IUS), 2014
external identifiers
  • WOS:000352792500107
  • Scopus:84910026556
DOI
10.1109/ULTSYM.2014.0107
language
English
LU publication?
yes
id
ae845d92-0da9-4f31-95ca-49f7a19195b0 (old id 5401204)
date added to LUP
2015-05-19 11:21:18
date last changed
2017-01-01 07:59:27
@inproceedings{ae845d92-0da9-4f31-95ca-49f7a19195b0,
  abstract     = {The Wall Shear Rate (WSR) represents an important parameter correlated with cardiovascular diseases, like, for example the atherosclerotic plaque formation. The WSR can be obtained as the radial blood velocity gradient assessed in the wall proximity. The WSR is typically approximated by using flow models like Poiseuille and/or Womersley applied to the measured center-line velocity. However these models cannot account for the complex flow configurations generated by the real geometry of the vessel, and the WSR estimate is inaccurate. The direct measurement of the velocity gradient through a Doppler high-resolution multigate technique can achieve a better accuracy, but the signal near the wall is affected by clutter. In this work an improved velocity reconstruction method for WSR measurement is proposed. It is based on the measurement of the actual velocity profile and a two-step interpolation that reconstructs the velocity in the wall proximity. The method, verified through realistic multiphysics simulations of a carotid artery, achieves a 5% RMS error for velocity reconstruction and a -10.5% underestimation in WSR assessment. The method was also tested on 14 healthy volunteers.},
  author       = {Ricci, S. and Swillens, A. and Ramalli, A. and Cinthio, Magnus and Segers, P. and Tortoli, P.},
  booktitle    = {2014 IEEE International Ultrasonics Symposium (IUS)},
  keyword      = {Wall Shear Rate,Multiphysics Simulations,Blood Velocity Profile},
  language     = {eng},
  pages        = {432--435},
  publisher    = {IEEE--Institute of Electrical and Electronics Engineers Inc.},
  title        = {Improved Wall Shear Rate Method for Robust Measurements},
  url          = {http://dx.doi.org/10.1109/ULTSYM.2014.0107},
  year         = {2014},
}