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Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.

Björkman, Per LU orcid ; Flamholc, Leo LU ; Molnegren, Vilma ; Marshall, Aline LU ; Guner, Nuray and Widell, Anders LU (2007) In AIDS 21(12). p.1641-1643
Abstract
In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
AIDS
volume
21
issue
12
pages
1641 - 1643
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000248495400019
  • scopus:34447573625
  • pmid:17630561
ISSN
1473-5571
DOI
10.1097/QAD.0b013e32823bc9b7
language
English
LU publication?
yes
id
727686f8-ffc4-4d2a-a6ab-9021e86e9485 (old id 540749)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17630561&dopt=Abstract
date added to LUP
2016-04-04 08:14:42
date last changed
2022-03-15 07:52:08
@article{727686f8-ffc4-4d2a-a6ab-9021e86e9485,
  abstract     = {{In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P &lt; 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.}},
  author       = {{Björkman, Per and Flamholc, Leo and Molnegren, Vilma and Marshall, Aline and Guner, Nuray and Widell, Anders}},
  issn         = {{1473-5571}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1641--1643}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{AIDS}},
  title        = {{Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.}},
  url          = {{http://dx.doi.org/10.1097/QAD.0b013e32823bc9b7}},
  doi          = {{10.1097/QAD.0b013e32823bc9b7}},
  volume       = {{21}},
  year         = {{2007}},
}