Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.
(2007) In AIDS 21(12). p.1641-1643- Abstract
- In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/540749
- author
- Björkman, Per LU ; Flamholc, Leo LU ; Molnegren, Vilma ; Marshall, Aline LU ; Guner, Nuray and Widell, Anders LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- AIDS
- volume
- 21
- issue
- 12
- pages
- 1641 - 1643
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000248495400019
- scopus:34447573625
- pmid:17630561
- ISSN
- 1473-5571
- DOI
- 10.1097/QAD.0b013e32823bc9b7
- language
- English
- LU publication?
- yes
- id
- 727686f8-ffc4-4d2a-a6ab-9021e86e9485 (old id 540749)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17630561&dopt=Abstract
- date added to LUP
- 2016-04-04 08:14:42
- date last changed
- 2022-03-15 07:52:08
@article{727686f8-ffc4-4d2a-a6ab-9021e86e9485, abstract = {{In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.}}, author = {{Björkman, Per and Flamholc, Leo and Molnegren, Vilma and Marshall, Aline and Guner, Nuray and Widell, Anders}}, issn = {{1473-5571}}, language = {{eng}}, number = {{12}}, pages = {{1641--1643}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{AIDS}}, title = {{Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.}}, url = {{http://dx.doi.org/10.1097/QAD.0b013e32823bc9b7}}, doi = {{10.1097/QAD.0b013e32823bc9b7}}, volume = {{21}}, year = {{2007}}, }