Advanced

Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.

Björkman, Per LU ; Flamholc, Leo LU ; Molnegren, Vilma; Marshall, Aline LU ; Guner, Nuray and Widell, Anders LU (2007) In AIDS 21(12). p.1641-1643
Abstract
In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
AIDS
volume
21
issue
12
pages
1641 - 1643
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000248495400019
  • scopus:34447573625
ISSN
1473-5571
DOI
10.1097/QAD.0b013e32823bc9b7
language
English
LU publication?
yes
id
727686f8-ffc4-4d2a-a6ab-9021e86e9485 (old id 540749)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17630561&dopt=Abstract
date added to LUP
2007-12-10 14:30:38
date last changed
2017-11-19 04:17:53
@article{727686f8-ffc4-4d2a-a6ab-9021e86e9485,
  abstract     = {In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P &lt; 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.},
  author       = {Björkman, Per and Flamholc, Leo and Molnegren, Vilma and Marshall, Aline and Guner, Nuray and Widell, Anders},
  issn         = {1473-5571},
  language     = {eng},
  number       = {12},
  pages        = {1641--1643},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {AIDS},
  title        = {Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.},
  url          = {http://dx.doi.org/10.1097/QAD.0b013e32823bc9b7},
  volume       = {21},
  year         = {2007},
}