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Discordant HER2 overexpression in primary and metastatic upper gastrointestinal adenocarcinoma signifies poor prognosis.

Hedner, Charlotta LU ; Tran, Lena; Borg, David LU ; Nodin, Björn LU ; Jirström, Karin LU and Eberhard, Jakob LU (2015) In Histopathology
Abstract
Targeted therapy with trastuzumab has proven to be effective for patients with gastric cancer overexpressing the human epidermal growth factor receptor 2 (HER2). Further studies are needed to determine the best method for assessment of HER2 overexpression. Moreover, the prognostic value of HER2 overexpression, including the significance of tumour heterogeneity, remains unclear.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Histopathology
publisher
Wiley-Blackwell
external identifiers
  • pmid:26016514
  • scopus:84955203043
ISSN
0309-0167
DOI
10.1111/his.12744
language
English
LU publication?
yes
id
2925b5f3-6080-4594-a782-ed02f25df724 (old id 5442112)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26016514?dopt=Abstract
date added to LUP
2015-06-05 15:35:34
date last changed
2017-07-02 04:32:58
@article{2925b5f3-6080-4594-a782-ed02f25df724,
  abstract     = {Targeted therapy with trastuzumab has proven to be effective for patients with gastric cancer overexpressing the human epidermal growth factor receptor 2 (HER2). Further studies are needed to determine the best method for assessment of HER2 overexpression. Moreover, the prognostic value of HER2 overexpression, including the significance of tumour heterogeneity, remains unclear.},
  author       = {Hedner, Charlotta and Tran, Lena and Borg, David and Nodin, Björn and Jirström, Karin and Eberhard, Jakob},
  issn         = {0309-0167},
  language     = {eng},
  month        = {05},
  publisher    = {Wiley-Blackwell},
  series       = {Histopathology},
  title        = {Discordant HER2 overexpression in primary and metastatic upper gastrointestinal adenocarcinoma signifies poor prognosis.},
  url          = {http://dx.doi.org/10.1111/his.12744},
  year         = {2015},
}