Assessment of human sinus cavity air volume using tunable diode laser spectroscopy, with application to sinusitis diagnostics.
(2015) In Journal of Biophotonics 8(11-12). p.985-992- Abstract
- Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over-prescription of antibiotics. A non-intrusive optical technique called GASMAS (GAs in Scattering Media Absorption Spectroscopy), which has a true potential of being developed into an important complement to other means of detection, was utilized in this work. Water vapor in the frontal sinuses, related to the free gas volume, was studied at around 937 nm in healthy volunteers. The results show a good stability of the GASMAS signals over extended times for the frontal sinuses for all volunteers, showing promising applicability to detect anomalies due to sinusitis. Measurements were also performed following the application of a... (More)
- Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over-prescription of antibiotics. A non-intrusive optical technique called GASMAS (GAs in Scattering Media Absorption Spectroscopy), which has a true potential of being developed into an important complement to other means of detection, was utilized in this work. Water vapor in the frontal sinuses, related to the free gas volume, was studied at around 937 nm in healthy volunteers. The results show a good stability of the GASMAS signals over extended times for the frontal sinuses for all volunteers, showing promising applicability to detect anomalies due to sinusitis. Measurements were also performed following the application of a decongestion spray. No noticeable signal change was observed, which is consistent with the fact that the water vapor concentration is given by the temperature only, and is not influenced by changes in cavity ventilation. Evaluated GASMAS data recorded on 6 consecutive days show signal stability for the left and right frontal sinus in one of the test volonteers. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5448608
- author
- Huang, Jing ; Zhang, Hao ; Li, Tianqi ; Lin, Huiying ; Svanberg, Katarina LU and Svanberg, Sune LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Biophotonics
- volume
- 8
- issue
- 11-12
- pages
- 985 - 992
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:25990508
- wos:000364317500015
- scopus:84946475470
- pmid:25990508
- ISSN
- 1864-063X
- DOI
- 10.1002/jbio.201500110
- language
- English
- LU publication?
- yes
- id
- e1f06f9d-14e8-4293-8d0d-6ba6130e3dec (old id 5448608)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25990508?dopt=Abstract
- date added to LUP
- 2016-04-01 10:30:48
- date last changed
- 2022-04-27 22:47:36
@article{e1f06f9d-14e8-4293-8d0d-6ba6130e3dec,
abstract = {{Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over-prescription of antibiotics. A non-intrusive optical technique called GASMAS (GAs in Scattering Media Absorption Spectroscopy), which has a true potential of being developed into an important complement to other means of detection, was utilized in this work. Water vapor in the frontal sinuses, related to the free gas volume, was studied at around 937 nm in healthy volunteers. The results show a good stability of the GASMAS signals over extended times for the frontal sinuses for all volunteers, showing promising applicability to detect anomalies due to sinusitis. Measurements were also performed following the application of a decongestion spray. No noticeable signal change was observed, which is consistent with the fact that the water vapor concentration is given by the temperature only, and is not influenced by changes in cavity ventilation. Evaluated GASMAS data recorded on 6 consecutive days show signal stability for the left and right frontal sinus in one of the test volonteers.}},
author = {{Huang, Jing and Zhang, Hao and Li, Tianqi and Lin, Huiying and Svanberg, Katarina and Svanberg, Sune}},
issn = {{1864-063X}},
language = {{eng}},
number = {{11-12}},
pages = {{985--992}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Biophotonics}},
title = {{Assessment of human sinus cavity air volume using tunable diode laser spectroscopy, with application to sinusitis diagnostics.}},
url = {{http://dx.doi.org/10.1002/jbio.201500110}},
doi = {{10.1002/jbio.201500110}},
volume = {{8}},
year = {{2015}},
}