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Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Jansen, Willemijn J; Ossenkoppele, Rik; Knol, Dirk L; Tijms, Betty M; Scheltens, Philip; Verhey, Frans R J; Visser, Pieter Jelle; Aalten, Pauline; Aarsland, Dag and Alcolea, Daniel, et al. (2015) In JAMA: the journal of the American Medical Association 313(19). p.1924-1938
Abstract
Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.
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keywords
Amyloid beta-Peptides: analysis, Apolipoprotein E4: genetics, Biological Markers: analysis, Brain: pathology, Cerebrospinal Fluid: chemistry, Dementia: pathology, Mild Cognitive Impairment: pathology
in
JAMA: the journal of the American Medical Association
volume
313
issue
19
pages
1924 - 1938
publisher
American Medical Association
external identifiers
  • pmid:25988462
  • scopus:84937529452
ISSN
1538-3598
DOI
10.1001/jama.2015.4668
language
English
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yes
id
47e3f210-d8b1-42e3-b41d-96583ba93671 (old id 5448655)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25988462?dopt=Abstract
date added to LUP
2015-06-07 00:13:50
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2017-11-05 03:52:06
@article{47e3f210-d8b1-42e3-b41d-96583ba93671,
  abstract     = {Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.},
  author       = {Jansen, Willemijn J and Ossenkoppele, Rik and Knol, Dirk L and Tijms, Betty M and Scheltens, Philip and Verhey, Frans R J and Visser, Pieter Jelle and Aalten, Pauline and Aarsland, Dag and Alcolea, Daniel and Alexander, Myriam and Almdahl, Ina S and Arnold, Steven E and Baldeiras, Inês and Barthel, Henryk and van Berckel, Bart N M and Bibeau, Kristen and Blennow, Kaj and Brooks, David J and van Buchem, Mark A and Camus, Vincent and Cavedo, Enrica and Chen, Kewei and Chetelat, Gael and Cohen, Ann D and Drzezga, Alexander and Engelborghs, Sebastiaan and Fagan, Anne M and Fladby, Tormod and Fleisher, Adam S and van der Flier, Wiesje M and Ford, Lisa and Förster, Stefan and Fortea, Juan and Foskett, Nadia and Frederiksen, Kristian S and Freund-Levi, Yvonne and Frisoni, Giovanni B and Froelich, Lutz and Gabryelewicz, Tomasz and Gill, Kiran Dip and Gkatzima, Olymbia and Gómez-Tortosa, Estrella and Gordon, Mark Forrest and Grimmer, Timo and Hampel, Harald and Hausner, Lucrezia and Hellwig, Sabine and Herukka, Sanna-Kaisa and Hildebrandt, Helmut and Ishihara, Lianna and Ivanoiu, Adrian and Jagust, William J and Johannsen, Peter and Kandimalla, Ramesh and Kapaki, Elisabeth and Klimkowicz-Mrowiec, Aleksandra and Klunk, William E and Köhler, Sebastian and Koglin, Norman and Kornhuber, Johannes and Kramberger, Milica G and Van Laere, Koen and Landau, Susan M and Lee, Dong Young and de Leon, Mony and Lisetti, Viviana and Lleó, Alberto and Madsen, Karine and Maier, Wolfgang and Marcusson, Jan and Mattsson, Niklas and de Mendonça, Alexandre and Meulenbroek, Olga and Meyer, Philipp T and Mintun, Mark A and Mok, Vincent and Molinuevo, José Luis and Møllergård, Hanne M and Morris, John C and Mroczko, Barbara and Van der Mussele, Stefan and Na, Duk L and Newberg, Andrew and Nordberg, Agneta and Nordlund, Arto and Novak, Gerald P and Paraskevas, George P and Parnetti, Lucilla and Perera, Gayan and Peters, Oliver and Popp, Julius and Prabhakar, Sudesh and Rabinovici, Gil D and Ramakers, Inez H G B and Rami, Lorena and Resende de Oliveira, Catarina and Rinne, Juha O and Rodrigue, Karen M and Rodríguez-Rodríguez, Eloy and Roe, Catherine M and Rot, Uros and Rowe, Christopher C and Rüther, Eckart and Sabri, Osama and Sanchez-Juan, Páscual and Santana, Isabel and Sarazin, Marie and Schröder, Johannes and Schütte, Christin and Seo, Sang W and Soetewey, Femke and Soininen, Hilkka and Spiru, Luiza and Struyfs, Hanne and Teunissen, Charlotte E and Tsolaki, Magda and Vandenberghe, Rik and Verbeek, Marcel M and Villemagne, Victor L and Vos, Stephanie J B and van Waalwijk van Doorn, Linda J C and Waldemar, Gunhild and Wallin, Anders and Wallin, Åsa and Wiltfang, Jens and Wolk, David A and Zboch, Marzena and Zetterberg, Henrik},
  issn         = {1538-3598},
  keyword      = {Amyloid beta-Peptides: analysis,Apolipoprotein E4: genetics,Biological Markers: analysis,Brain: pathology,Cerebrospinal Fluid: chemistry,Dementia: pathology,Mild Cognitive Impairment: pathology},
  language     = {eng},
  number       = {19},
  pages        = {1924--1938},
  publisher    = {American Medical Association},
  series       = {JAMA: the journal of the American Medical Association},
  title        = {Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.},
  url          = {http://dx.doi.org/10.1001/jama.2015.4668},
  volume       = {313},
  year         = {2015},
}