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Pitfalls in soft tissue cytopathology

Rekhi, Bharat ; Qian, Xiaohua ; Domanski, Henryk A. LU ; Klijanienko, Jerzy and Field, Andrew (2024) In Cytopathology 35(1). p.30-47
Abstract

Fine needle aspiration biopsy (FNAB) is a diagnostic modality for the evaluation of suspicious soft tissue masses. Despite its reasonable sensitivity, specificity and positive predictive value in differentiating benign from malignant neoplasms, the exact subtyping of the primary soft tissue tumours can be challenging. Certain tumours constitute “pitfalls” and add to the diagnostic challenge. This review provides a detailed account of the diagnostic challenges in soft tissue cytopathology, including pitfalls and, more importantly, the ways to overcome these challenges by integrating clinical details, key cytomorphological features and judicious application of ancillary techniques.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
FNAB, pitfalls, soft tissue cytopathology, soft tissue neoplasms
in
Cytopathology
volume
35
issue
1
pages
30 - 47
publisher
Wiley-Blackwell
external identifiers
  • pmid:37548096
  • scopus:85166919708
ISSN
0956-5507
DOI
10.1111/cyt.13282
language
English
LU publication?
yes
id
548d3975-e4f7-4012-9394-fdf67673d763
date added to LUP
2023-11-16 15:01:30
date last changed
2024-04-14 04:43:04
@article{548d3975-e4f7-4012-9394-fdf67673d763,
  abstract     = {{<p>Fine needle aspiration biopsy (FNAB) is a diagnostic modality for the evaluation of suspicious soft tissue masses. Despite its reasonable sensitivity, specificity and positive predictive value in differentiating benign from malignant neoplasms, the exact subtyping of the primary soft tissue tumours can be challenging. Certain tumours constitute “pitfalls” and add to the diagnostic challenge. This review provides a detailed account of the diagnostic challenges in soft tissue cytopathology, including pitfalls and, more importantly, the ways to overcome these challenges by integrating clinical details, key cytomorphological features and judicious application of ancillary techniques.</p>}},
  author       = {{Rekhi, Bharat and Qian, Xiaohua and Domanski, Henryk A. and Klijanienko, Jerzy and Field, Andrew}},
  issn         = {{0956-5507}},
  keywords     = {{FNAB; pitfalls; soft tissue cytopathology; soft tissue neoplasms}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{30--47}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Cytopathology}},
  title        = {{Pitfalls in soft tissue cytopathology}},
  url          = {{http://dx.doi.org/10.1111/cyt.13282}},
  doi          = {{10.1111/cyt.13282}},
  volume       = {{35}},
  year         = {{2024}},
}