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Filling the Gap – Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient : A European Consensus View

Wehling, M.; Ashton, C.; Ekpo, E.; Gwynn, S.; Laville, M.; Olsson, K. LU and Spring, M. (2017) In Drug Research 67(1). p.5-12
Abstract

Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group. Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general practitioners and other doctors to test agreement at the European level. Results: 64 responses were evaluated from around Europe. Agreement was achieved in 86% of the statements following amendment and redistribution of 6 of the statements. The survey and its feedback prompted the development of 13 recommendations related to the diagnosis and... (More)

Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group. Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general practitioners and other doctors to test agreement at the European level. Results: 64 responses were evaluated from around Europe. Agreement was achieved in 86% of the statements following amendment and redistribution of 6 of the statements. The survey and its feedback prompted the development of 13 recommendations related to the diagnosis and treatment of hyponatraemia including SIADH. Conclusion: The series of 13 recommendations developed here is intended to increase clarity for clinicians managing older patients with hyponatraemia and SIADH. Surprisingly, despite the lack of clear guidelines or recommendations for this age group consensus levels for the author-based statements were high among the respondents.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
algorithms, geriatric pharmacotherapy, hyponatraemia, older patients, SIADH
in
Drug Research
volume
67
issue
1
pages
5 - 12
publisher
Georg Thieme Verlag
external identifiers
  • scopus:84990190770
  • wos:000393909100001
ISSN
2194-9379
DOI
10.1055/s-0042-115015
language
English
LU publication?
yes
id
548edbc5-bee0-4f3e-9f0c-dc515daef6e4
date added to LUP
2016-12-07 13:10:18
date last changed
2018-01-21 04:17:41
@article{548edbc5-bee0-4f3e-9f0c-dc515daef6e4,
  abstract     = {<p> Introduction: Causes of hyponatraemia in older patients are multivariate and in the case of SIADH may often be drug induced. Diagnostic and treatment algorithms are unclear for this important age group. Methods: The author group identified 6 broad themes for consensus and formulated 42 separate consensus statements within these 6 themes. Statements were then circulated to geriatricians, general practitioners and other doctors to test agreement at the European level. Results: 64 responses were evaluated from around Europe. Agreement was achieved in 86% of the statements following amendment and redistribution of 6 of the statements. The survey and its feedback prompted the development of 13 recommendations related to the diagnosis and treatment of hyponatraemia including SIADH. Conclusion: The series of 13 recommendations developed here is intended to increase clarity for clinicians managing older patients with hyponatraemia and SIADH. Surprisingly, despite the lack of clear guidelines or recommendations for this age group consensus levels for the author-based statements were high among the respondents.</p>},
  author       = {Wehling, M. and Ashton, C. and Ekpo, E. and Gwynn, S. and Laville, M. and Olsson, K. and Spring, M.},
  issn         = {2194-9379},
  keyword      = {algorithms,geriatric pharmacotherapy,hyponatraemia,older patients,SIADH},
  language     = {eng},
  number       = {1},
  pages        = {5--12},
  publisher    = {Georg Thieme Verlag},
  series       = {Drug Research},
  title        = {Filling the Gap – Improving Awareness and Practice in Hyponatraemia and the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) in the Older Patient : A European Consensus View},
  url          = {http://dx.doi.org/10.1055/s-0042-115015},
  volume       = {67},
  year         = {2017},
}