Asexuals, Polyploids, Evolutionary Opportunists ...: The Population Genetics of Positive but Deteriorating Mutations.
(2012) In Genetics 191(4). p.499-1393- Abstract
- Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2608761
- author
- Bengtsson, Bengt Olle LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- mutation, mutational load, probability of fixation, selecttion
- in
- Genetics
- volume
- 191
- issue
- 4
- pages
- 499 - 1393
- publisher
- Genetics Society of America
- external identifiers
-
- wos:000309000500028
- pmid:22595245
- scopus:84865083724
- pmid:22595245
- ISSN
- 0016-6731
- DOI
- 10.1534/genetics.112.140715
- language
- English
- LU publication?
- yes
- id
- 54f9895c-590f-4340-be79-77a385f2f317 (old id 2608761)
- date added to LUP
- 2016-04-01 11:01:19
- date last changed
- 2022-01-26 04:48:12
@article{54f9895c-590f-4340-be79-77a385f2f317, abstract = {{Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.}}, author = {{Bengtsson, Bengt Olle}}, issn = {{0016-6731}}, keywords = {{mutation; mutational load; probability of fixation; selecttion}}, language = {{eng}}, number = {{4}}, pages = {{499--1393}}, publisher = {{Genetics Society of America}}, series = {{Genetics}}, title = {{Asexuals, Polyploids, Evolutionary Opportunists ...: The Population Genetics of Positive but Deteriorating Mutations.}}, url = {{http://dx.doi.org/10.1534/genetics.112.140715}}, doi = {{10.1534/genetics.112.140715}}, volume = {{191}}, year = {{2012}}, }