Prevalence of contact allergies in the population compared to a tertiary referral patch test clinic in Jena/Germany
(2021) In Contact Dermatitis 85(5). p.563-571- Abstract
Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University... (More)
Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University Hospital Department; of these 1694 (83.2%) with the German baseline series using pet./aq.-based, investigator-loaded allergens. Results: In the population (clinical) sample, 19.6% (41.1%) were sensitized to at least one of the allergens considered. The most common baseline series allergens in the population/clinical sample were nickel (10.5%/13.2%), fragrance mix (FM) II (2.9%/6.7%), FM I (2.3%/8.3%), and cobalt (1.6%/5%). The clinical sample was slightly older (71.5% vs 55.9% age 40+) and included less males (36% vs 49.3%). Conclusions: Results are quite similar, although prevalences are usually higher in the clinical setting, with the exception of p-tert-butylphenol formaldehyde resin.
(Less)
- author
- Uter, Wolfgang ; Zetzmann, Anica ; Ofenloch, Robert ; Schliemann, Sibylle ; Bruze, Magnus LU ; Gonçalo, Margarida ; Naldi, Luigi ; Schuttelaar, Marie Louise A. ; Svensson, Åke LU and Elsner, Peter
- author collaboration
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- clinical epidemiology, contact allergy, epidemiology, patch testing, RRID:SCR_001905, surveillance
- in
- Contact Dermatitis
- volume
- 85
- issue
- 5
- pages
- 563 - 571
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85111629955
- pmid:34184275
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.13923
- language
- English
- LU publication?
- yes
- id
- 5506ec57-9b90-4710-8116-736c3c6f8811
- date added to LUP
- 2021-08-30 11:16:10
- date last changed
- 2025-10-20 21:32:15
@article{5506ec57-9b90-4710-8116-736c3c6f8811,
abstract = {{<p>Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University Hospital Department; of these 1694 (83.2%) with the German baseline series using pet./aq.-based, investigator-loaded allergens. Results: In the population (clinical) sample, 19.6% (41.1%) were sensitized to at least one of the allergens considered. The most common baseline series allergens in the population/clinical sample were nickel (10.5%/13.2%), fragrance mix (FM) II (2.9%/6.7%), FM I (2.3%/8.3%), and cobalt (1.6%/5%). The clinical sample was slightly older (71.5% vs 55.9% age 40+) and included less males (36% vs 49.3%). Conclusions: Results are quite similar, although prevalences are usually higher in the clinical setting, with the exception of p-tert-butylphenol formaldehyde resin.</p>}},
author = {{Uter, Wolfgang and Zetzmann, Anica and Ofenloch, Robert and Schliemann, Sibylle and Bruze, Magnus and Gonçalo, Margarida and Naldi, Luigi and Schuttelaar, Marie Louise A. and Svensson, Åke and Elsner, Peter}},
issn = {{0105-1873}},
keywords = {{clinical epidemiology; contact allergy; epidemiology; patch testing; RRID:SCR_001905; surveillance}},
language = {{eng}},
number = {{5}},
pages = {{563--571}},
publisher = {{Wiley-Blackwell}},
series = {{Contact Dermatitis}},
title = {{Prevalence of contact allergies in the population compared to a tertiary referral patch test clinic in Jena/Germany}},
url = {{http://dx.doi.org/10.1111/cod.13923}},
doi = {{10.1111/cod.13923}},
volume = {{85}},
year = {{2021}},
}