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Prevalence of contact allergies in the population compared to a tertiary referral patch test clinic in Jena/Germany

Uter, Wolfgang ; Zetzmann, Anica ; Ofenloch, Robert ; Schliemann, Sibylle ; Bruze, Magnus LU ; Gonçalo, Margarida ; Naldi, Luigi ; Schuttelaar, Marie Louise A. ; Svensson, Åke LU and Elsner, Peter (2021) In Contact Dermatitis 85(5). p.563-571
Abstract

Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University... (More)

Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University Hospital Department; of these 1694 (83.2%) with the German baseline series using pet./aq.-based, investigator-loaded allergens. Results: In the population (clinical) sample, 19.6% (41.1%) were sensitized to at least one of the allergens considered. The most common baseline series allergens in the population/clinical sample were nickel (10.5%/13.2%), fragrance mix (FM) II (2.9%/6.7%), FM I (2.3%/8.3%), and cobalt (1.6%/5%). The clinical sample was slightly older (71.5% vs 55.9% age 40+) and included less males (36% vs 49.3%). Conclusions: Results are quite similar, although prevalences are usually higher in the clinical setting, with the exception of p-tert-butylphenol formaldehyde resin.

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author
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author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
clinical epidemiology, contact allergy, epidemiology, patch testing, RRID:SCR_001905, surveillance
in
Contact Dermatitis
volume
85
issue
5
pages
563 - 571
publisher
Wiley-Blackwell
external identifiers
  • scopus:85111629955
  • pmid:34184275
ISSN
0105-1873
DOI
10.1111/cod.13923
language
English
LU publication?
yes
id
5506ec57-9b90-4710-8116-736c3c6f8811
date added to LUP
2021-08-30 11:16:10
date last changed
2024-06-01 14:36:19
@article{5506ec57-9b90-4710-8116-736c3c6f8811,
  abstract     = {{<p>Background: The contact allergy prevalences in patch-tested patients are usually higher than those in the population, owing to morbidity-driven selection. Objectives: To examine the differences between two samples, one from the population, one from the patch test clinic, in one area of Germany (Jena, Thuringia). Methods: Between August 2008 and October 2011, a total of 519 participants of the population-based european dermato-epidemiology network (EDEN) fragrance study were patch tested in Jena using a TRUE Test baseline series extended with some pet.-based (fragrance) allergen preparations. Between 2007 and 2012 (inclusive), 1906 routine patients were patch tested for suspected allergic contact dermatitis (ACD) in the Jena University Hospital Department; of these 1694 (83.2%) with the German baseline series using pet./aq.-based, investigator-loaded allergens. Results: In the population (clinical) sample, 19.6% (41.1%) were sensitized to at least one of the allergens considered. The most common baseline series allergens in the population/clinical sample were nickel (10.5%/13.2%), fragrance mix (FM) II (2.9%/6.7%), FM I (2.3%/8.3%), and cobalt (1.6%/5%). The clinical sample was slightly older (71.5% vs 55.9% age 40+) and included less males (36% vs 49.3%). Conclusions: Results are quite similar, although prevalences are usually higher in the clinical setting, with the exception of p-tert-butylphenol formaldehyde resin.</p>}},
  author       = {{Uter, Wolfgang and Zetzmann, Anica and Ofenloch, Robert and Schliemann, Sibylle and Bruze, Magnus and Gonçalo, Margarida and Naldi, Luigi and Schuttelaar, Marie Louise A. and Svensson, Åke and Elsner, Peter}},
  issn         = {{0105-1873}},
  keywords     = {{clinical epidemiology; contact allergy; epidemiology; patch testing; RRID:SCR_001905; surveillance}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{563--571}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Prevalence of contact allergies in the population compared to a tertiary referral patch test clinic in Jena/Germany}},
  url          = {{http://dx.doi.org/10.1111/cod.13923}},
  doi          = {{10.1111/cod.13923}},
  volume       = {{85}},
  year         = {{2021}},
}