Pallidal and thalamic neurostimulation in severe tardive dystonia
(2001) In Journal of Neurology, Neurosurgery and Psychiatry 70(4). p.9-557- Abstract
A 70 year old woman presented with a 6 year history of medically refractory severe tardive dystonia. After informed consent, a bilateral stereotactic electrode placement targeting the ventral intermediate thalamic nucleus (VIM) and the globus pallidus internus (GPi) was performed. After bilateral stimulation of the GPi, the patient showed a clear and stable improvement of the painful dystonic syndrome within hours. Stimulation of the VIM did not improve the hyperkinetic movements and simultaneous stimulation of both the GPi and the VIM did not result in any additional benefit. The possible pathophysiological mechanisms are discussed.
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- author
- Trottenberg, T ; Paul, G LU ; Meissner, Wlodzimierz ; Maier-Hauff, K ; Taschner, C and Kupsch, A
- publishing date
- 2001-04
- type
- Contribution to journal
- publication status
- published
- keywords
- Aged, Dystonia, Electric Stimulation Therapy, Female, Globus Pallidus, Humans, Ventral Thalamic Nuclei, Case Reports, Journal Article
- in
- Journal of Neurology, Neurosurgery and Psychiatry
- volume
- 70
- issue
- 4
- pages
- 3 pages
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:11254790
- scopus:0035060183
- ISSN
- 0022-3050
- language
- English
- LU publication?
- no
- id
- 558190f5-53dc-4741-8c08-a3b501dd453a
- date added to LUP
- 2017-05-18 12:47:21
- date last changed
- 2024-09-02 00:36:12
@article{558190f5-53dc-4741-8c08-a3b501dd453a, abstract = {{<p>A 70 year old woman presented with a 6 year history of medically refractory severe tardive dystonia. After informed consent, a bilateral stereotactic electrode placement targeting the ventral intermediate thalamic nucleus (VIM) and the globus pallidus internus (GPi) was performed. After bilateral stimulation of the GPi, the patient showed a clear and stable improvement of the painful dystonic syndrome within hours. Stimulation of the VIM did not improve the hyperkinetic movements and simultaneous stimulation of both the GPi and the VIM did not result in any additional benefit. The possible pathophysiological mechanisms are discussed.</p>}}, author = {{Trottenberg, T and Paul, G and Meissner, Wlodzimierz and Maier-Hauff, K and Taschner, C and Kupsch, A}}, issn = {{0022-3050}}, keywords = {{Aged; Dystonia; Electric Stimulation Therapy; Female; Globus Pallidus; Humans; Ventral Thalamic Nuclei; Case Reports; Journal Article}}, language = {{eng}}, number = {{4}}, pages = {{9--557}}, publisher = {{BMJ Publishing Group}}, series = {{Journal of Neurology, Neurosurgery and Psychiatry}}, title = {{Pallidal and thalamic neurostimulation in severe tardive dystonia}}, volume = {{70}}, year = {{2001}}, }