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Pallidal and thalamic neurostimulation in severe tardive dystonia

Trottenberg, T; Paul, G LU ; Meissner, Wlodzimierz; Maier-Hauff, K; Taschner, C and Kupsch, A (2001) In Journal of Neurology, Neurosurgery and Psychiatry 70(4). p.9-557
Abstract

A 70 year old woman presented with a 6 year history of medically refractory severe tardive dystonia. After informed consent, a bilateral stereotactic electrode placement targeting the ventral intermediate thalamic nucleus (VIM) and the globus pallidus internus (GPi) was performed. After bilateral stimulation of the GPi, the patient showed a clear and stable improvement of the painful dystonic syndrome within hours. Stimulation of the VIM did not improve the hyperkinetic movements and simultaneous stimulation of both the GPi and the VIM did not result in any additional benefit. The possible pathophysiological mechanisms are discussed.

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author
publishing date
type
Contribution to journal
publication status
published
keywords
Aged, Dystonia, Electric Stimulation Therapy, Female, Globus Pallidus, Humans, Ventral Thalamic Nuclei, Case Reports, Journal Article
in
Journal of Neurology, Neurosurgery and Psychiatry
volume
70
issue
4
pages
3 pages
publisher
BMJ Publishing Group
external identifiers
  • scopus:0035060183
ISSN
0022-3050
language
English
LU publication?
no
id
558190f5-53dc-4741-8c08-a3b501dd453a
date added to LUP
2017-05-18 12:47:21
date last changed
2018-01-07 12:04:13
@article{558190f5-53dc-4741-8c08-a3b501dd453a,
  abstract     = {<p>A 70 year old woman presented with a 6 year history of medically refractory severe tardive dystonia. After informed consent, a bilateral stereotactic electrode placement targeting the ventral intermediate thalamic nucleus (VIM) and the globus pallidus internus (GPi) was performed. After bilateral stimulation of the GPi, the patient showed a clear and stable improvement of the painful dystonic syndrome within hours. Stimulation of the VIM did not improve the hyperkinetic movements and simultaneous stimulation of both the GPi and the VIM did not result in any additional benefit. The possible pathophysiological mechanisms are discussed.</p>},
  author       = {Trottenberg, T and Paul, G and Meissner, Wlodzimierz and Maier-Hauff, K and Taschner, C and Kupsch, A},
  issn         = {0022-3050},
  keyword      = {Aged,Dystonia,Electric Stimulation Therapy,Female,Globus Pallidus,Humans,Ventral Thalamic Nuclei,Case Reports,Journal Article},
  language     = {eng},
  number       = {4},
  pages        = {9--557},
  publisher    = {BMJ Publishing Group},
  series       = {Journal of Neurology, Neurosurgery and Psychiatry},
  title        = {Pallidal and thalamic neurostimulation in severe tardive dystonia},
  volume       = {70},
  year         = {2001},
}