Guiding motor-propelled molecules with nanoscale precision through silanized bi-channel structures
(2005) In Nanotechnology 16(6). p.710-717- Abstract
- We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service... (More)
- We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service channels, as is the venting of ADP and P-i (inorganic phosphorus). Channels of different widths (100-700 nm) and shapes are fabricated and measurements made on them. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/233742
- author
- Bunk, Richard LU ; Sundberg, M ; Mansson, A ; Nicholls, IA ; Omling, Pär LU ; Tagerud, S and Montelius, Lars LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nanotechnology
- volume
- 16
- issue
- 6
- pages
- 710 - 717
- publisher
- IOP Publishing
- external identifiers
-
- wos:000230144700014
- scopus:18744380653
- ISSN
- 0957-4484
- DOI
- 10.1088/0957-4484/16/6/014
- language
- English
- LU publication?
- yes
- id
- 55b9c1be-1b9e-4021-9c32-0642241d1750 (old id 233742)
- date added to LUP
- 2016-04-01 12:38:18
- date last changed
- 2022-01-27 07:50:24
@article{55b9c1be-1b9e-4021-9c32-0642241d1750,
abstract = {{We report on the design and fabrication of a channel structure for high precision guidance and achieving excellent confinement properties for motor-propelled molecular shuttles. The techniques used to manufacture the channel structure are mainly e-beam lithography and selective monolayer functionalization. The structure consists of two lateral layers of concentric channels on a SiO2 surface made biocompatible with the molecular motors. The quality and advantages of the design are demonstrated by experiments using the motor proteins actin and myosin. The special channel geometry leads to stable biochemical conditions with full motor protein functionality. ATP is sufficiently supplied to all parts of the structure by dedicated service channels, as is the venting of ADP and P-i (inorganic phosphorus). Channels of different widths (100-700 nm) and shapes are fabricated and measurements made on them.}},
author = {{Bunk, Richard and Sundberg, M and Mansson, A and Nicholls, IA and Omling, Pär and Tagerud, S and Montelius, Lars}},
issn = {{0957-4484}},
language = {{eng}},
number = {{6}},
pages = {{710--717}},
publisher = {{IOP Publishing}},
series = {{Nanotechnology}},
title = {{Guiding motor-propelled molecules with nanoscale precision through silanized bi-channel structures}},
url = {{http://dx.doi.org/10.1088/0957-4484/16/6/014}},
doi = {{10.1088/0957-4484/16/6/014}},
volume = {{16}},
year = {{2005}},
}