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Healthcare utilization patterns prior to a first heart failure diagnosis in a 90 day mortality cohort : A retrospective cohort study

Nilsson, Ellinore ; Pettersson, Louise LU orcid and Agvall, Björn LU orcid (2026) In International Journal of Cardiology: Cardiovascular Risk and Prevention 30.
Abstract

Background Early recognition of emerging heart failure prior to diagnosis could offer an opportunity for prevention-focused care, but it remains unclear whether healthcare seeking patterns before diagnosis indicate an earlier window for intervention. The objective was to determine if changes in utilization appeared during the 12-week pre-diagnosis period preceding a first diagnosis of heart failure with poor short-term prognosis. Methods A retrospective population-based study in Region Halland, Sweden, used the Regional Healthcare Information Platform to identify persons aged 40-90 years with incident heart failure during 2013 to 2019 who had died within 90 days. Encounters across inpatient and outpatient care settings, estimated... (More)

Background Early recognition of emerging heart failure prior to diagnosis could offer an opportunity for prevention-focused care, but it remains unclear whether healthcare seeking patterns before diagnosis indicate an earlier window for intervention. The objective was to determine if changes in utilization appeared during the 12-week pre-diagnosis period preceding a first diagnosis of heart failure with poor short-term prognosis. Methods A retrospective population-based study in Region Halland, Sweden, used the Regional Healthcare Information Platform to identify persons aged 40-90 years with incident heart failure during 2013 to 2019 who had died within 90 days. Encounters across inpatient and outpatient care settings, estimated glomerular filtration rate, N-terminal pro B type natriuretic peptide (NT-proBNP), echocardiography status and comorbidities were retrieved. Repeated measures analysis assessed trends in weekly visits during the 12-week lookback, with covariance analysis adjusted for age, sex, hypertension, ischemic heart disease and diabetes. Results The cohort included 902 individuals, mean age 85 years, 52% women. Echocardiography was not registered in 65%. Mean NT-proBNP measured 11,210 ng/L. The total average number of visits per week increased from 0.42 at week minus 12 to 1.77 at week 0 (p < 0.001). Primary care visits had increased from 0.30 to 0.72 (p < 0.001). Adjustments did not alter the pattern. No consistent early rise in visits appeared before the final two weeks. Conclusions In this high-mortality population, healthcare utilization remained low and unchanged until a sharp rise immediately before diagnosis, indicating a narrow and late window for preventive action, which limits the feasibility of preventive intervention in routine care.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Healthcare utilization, Healthcare-seeking behavior, Heart failure, Mortality, Primary care
in
International Journal of Cardiology: Cardiovascular Risk and Prevention
volume
30
article number
200678
publisher
Elsevier
external identifiers
  • pmid:42473582
  • scopus:105044209109
ISSN
2772-4875
DOI
10.1016/j.ijcrp.2026.200678
language
English
LU publication?
yes
id
55d79317-555e-44ea-a456-f8eda4f84705
date added to LUP
2026-09-30 16:13:08
date last changed
2026-10-01 03:00:03
@article{55d79317-555e-44ea-a456-f8eda4f84705,
  abstract     = {{<p>Background Early recognition of emerging heart failure prior to diagnosis could offer an opportunity for prevention-focused care, but it remains unclear whether healthcare seeking patterns before diagnosis indicate an earlier window for intervention. The objective was to determine if changes in utilization appeared during the 12-week pre-diagnosis period preceding a first diagnosis of heart failure with poor short-term prognosis. Methods A retrospective population-based study in Region Halland, Sweden, used the Regional Healthcare Information Platform to identify persons aged 40-90 years with incident heart failure during 2013 to 2019 who had died within 90 days. Encounters across inpatient and outpatient care settings, estimated glomerular filtration rate, N-terminal pro B type natriuretic peptide (NT-proBNP), echocardiography status and comorbidities were retrieved. Repeated measures analysis assessed trends in weekly visits during the 12-week lookback, with covariance analysis adjusted for age, sex, hypertension, ischemic heart disease and diabetes. Results The cohort included 902 individuals, mean age 85 years, 52% women. Echocardiography was not registered in 65%. Mean NT-proBNP measured 11,210 ng/L. The total average number of visits per week increased from 0.42 at week minus 12 to 1.77 at week 0 (p &lt; 0.001). Primary care visits had increased from 0.30 to 0.72 (p &lt; 0.001). Adjustments did not alter the pattern. No consistent early rise in visits appeared before the final two weeks. Conclusions In this high-mortality population, healthcare utilization remained low and unchanged until a sharp rise immediately before diagnosis, indicating a narrow and late window for preventive action, which limits the feasibility of preventive intervention in routine care.</p>}},
  author       = {{Nilsson, Ellinore and Pettersson, Louise and Agvall, Björn}},
  issn         = {{2772-4875}},
  keywords     = {{Healthcare utilization; Healthcare-seeking behavior; Heart failure; Mortality; Primary care}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{International Journal of Cardiology: Cardiovascular Risk and Prevention}},
  title        = {{Healthcare utilization patterns prior to a first heart failure diagnosis in a 90 day mortality cohort : A retrospective cohort study}},
  url          = {{http://dx.doi.org/10.1016/j.ijcrp.2026.200678}},
  doi          = {{10.1016/j.ijcrp.2026.200678}},
  volume       = {{30}},
  year         = {{2026}},
}