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Graphene and 2D-Like Nanomaterials : Different Biofunctionalization Pathways for Electrochemical Biosensor Development

Antiochia, Riccarda ; Tortolini, Cristina ; Tasca, Federico ; Gorton, Lo LU and Bollella, Paolo (2017) p.1-35
Abstract

In the last decades, nanotechnology has played a key role in the electrochemical biosensor development based on the mediated and direct electrochemical communication between the biorecognition elements and the electrode surface. In particular, graphene and 2D-like nanomaterials (e.g., boron nitride nanosheets, graphitic carbon nitride (g-C3N4) nanosheets, and various transition metal dichalcogenides) have attracted an increasing interest due to their peculiar properties such as high specific surface area and the ease of biofunctionalization. Moreover, in the last few years, the successful integration of graphene and 2D-like nanomaterials with other nanomaterials such as metal nanoparticles, metal oxides, or quantum... (More)

In the last decades, nanotechnology has played a key role in the electrochemical biosensor development based on the mediated and direct electrochemical communication between the biorecognition elements and the electrode surface. In particular, graphene and 2D-like nanomaterials (e.g., boron nitride nanosheets, graphitic carbon nitride (g-C3N4) nanosheets, and various transition metal dichalcogenides) have attracted an increasing interest due to their peculiar properties such as high specific surface area and the ease of biofunctionalization. Moreover, in the last few years, the successful integration of graphene and 2D-like nanomaterials with other nanomaterials such as metal nanoparticles, metal oxides, or quantum dots has dramatically increased the opportunities to develop novel electrochemical biosensors with highly enhanced performances, mainly due to the synergistic effects.In this chapter, we would like to give the state of art of graphene and 2D-like nanomaterials employment for electrochemical biosensors development, by critically discussing the advantages and drawbacks. Successively, the discussion should be separately addressed to three different cases: (1) redox enzyme immobilization, (2) antibody immobilization, and (3) DNA/aptamer immobilization. Finally, we should critically define for which cases graphene and 2D-like nanomaterials are the most suitable electrochemical platform, within some conclusion remarks and future perspectives of both kinds of nanomaterials.

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Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Biofunctionalization pathways, Electrochemical biosensors, Graphene, Graphene 2D-like nanomaterials (GLNs)
host publication
Graphene Bioelectronics
pages
35 pages
publisher
Elsevier
external identifiers
  • scopus:85054218843
ISBN
9780128133491
9780128133507
DOI
10.1016/B978-0-12-813349-1.00001-9
language
English
LU publication?
yes
id
567e10be-119c-4812-a33b-b82842b410a6
date added to LUP
2018-10-31 11:02:42
date last changed
2024-10-15 11:03:57
@inbook{567e10be-119c-4812-a33b-b82842b410a6,
  abstract     = {{<p>In the last decades, nanotechnology has played a key role in the electrochemical biosensor development based on the mediated and direct electrochemical communication between the biorecognition elements and the electrode surface. In particular, graphene and 2D-like nanomaterials (e.g., boron nitride nanosheets, graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>) nanosheets, and various transition metal dichalcogenides) have attracted an increasing interest due to their peculiar properties such as high specific surface area and the ease of biofunctionalization. Moreover, in the last few years, the successful integration of graphene and 2D-like nanomaterials with other nanomaterials such as metal nanoparticles, metal oxides, or quantum dots has dramatically increased the opportunities to develop novel electrochemical biosensors with highly enhanced performances, mainly due to the synergistic effects.In this chapter, we would like to give the state of art of graphene and 2D-like nanomaterials employment for electrochemical biosensors development, by critically discussing the advantages and drawbacks. Successively, the discussion should be separately addressed to three different cases: (1) redox enzyme immobilization, (2) antibody immobilization, and (3) DNA/aptamer immobilization. Finally, we should critically define for which cases graphene and 2D-like nanomaterials are the most suitable electrochemical platform, within some conclusion remarks and future perspectives of both kinds of nanomaterials.</p>}},
  author       = {{Antiochia, Riccarda and Tortolini, Cristina and Tasca, Federico and Gorton, Lo and Bollella, Paolo}},
  booktitle    = {{Graphene Bioelectronics}},
  isbn         = {{9780128133491}},
  keywords     = {{Biofunctionalization pathways; Electrochemical biosensors; Graphene; Graphene 2D-like nanomaterials (GLNs)}},
  language     = {{eng}},
  month        = {{11}},
  pages        = {{1--35}},
  publisher    = {{Elsevier}},
  title        = {{Graphene and 2D-Like Nanomaterials : Different Biofunctionalization Pathways for Electrochemical Biosensor Development}},
  url          = {{http://dx.doi.org/10.1016/B978-0-12-813349-1.00001-9}},
  doi          = {{10.1016/B978-0-12-813349-1.00001-9}},
  year         = {{2017}},
}