FDG-accumulating atherosclerotic plaques identified with 18F-FDG-PET/CT in 141 patients
(2009) In Molecular Imaging and Biology 11(6). p.9-455- Abstract
PURPOSE: The aim of this study was to describe the prevalence of atherosclerotic plaques based on [(18)F]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in a large population characterized by high risk of cardiovascular disease.
PROCEDURES: One hundred forty-one patients referred to our department for FDG-PET/CT for suspected lung cancer were re-evaluated for atherosclerotic lesions. Cardiovascular risk factors were analyzed based on patient records.
RESULTS: Forty-two percent of the patients had three cardiovascular risk factors or more. Nine percent of all plaques were assessed as active FDG-accumulating plaques, 88% were inactive calcified plaques, and 2% were mixed. The abdominal... (More)
PURPOSE: The aim of this study was to describe the prevalence of atherosclerotic plaques based on [(18)F]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in a large population characterized by high risk of cardiovascular disease.
PROCEDURES: One hundred forty-one patients referred to our department for FDG-PET/CT for suspected lung cancer were re-evaluated for atherosclerotic lesions. Cardiovascular risk factors were analyzed based on patient records.
RESULTS: Forty-two percent of the patients had three cardiovascular risk factors or more. Nine percent of all plaques were assessed as active FDG-accumulating plaques, 88% were inactive calcified plaques, and 2% were mixed. The abdominal aorta was the vessel with the highest plaque count. Patients with one risk factor had significantly less active and inactive plaques.
CONCLUSIONS: The observed association between the numbers of cardiovascular risk factors and the numbers of FDG-accumulating plaques as well as calcified plaques further supports the validity and value of FDG-PET/CT in the non-invasive identification and characterization of atherosclerotic disease.
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- author
- Wassélius, Johan A LU ; Larsson, Stig A LU and Jacobsson, Hans
- publishing date
- 2009-05-09
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Aged, Atherosclerosis, Calcinosis, Female, Fluorodeoxyglucose F18, Humans, Male, Positron-Emission Tomography, Radiopharmaceuticals, Risk Factors, Tomography, X-Ray Computed, Journal Article, Research Support, Non-U.S. Gov't
- in
- Molecular Imaging and Biology
- volume
- 11
- issue
- 6
- pages
- 5 pages
- publisher
- Springer
- external identifiers
-
- scopus:70350261795
- pmid:19424759
- ISSN
- 1536-1632
- DOI
- 10.1007/s11307-009-0223-2
- language
- English
- LU publication?
- no
- id
- 586f4806-072a-46c1-b5bc-ca2e9a9981cc
- date added to LUP
- 2016-10-14 09:56:30
- date last changed
- 2024-01-04 14:19:11
@article{586f4806-072a-46c1-b5bc-ca2e9a9981cc,
abstract = {{<p>PURPOSE: The aim of this study was to describe the prevalence of atherosclerotic plaques based on [(18)F]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in a large population characterized by high risk of cardiovascular disease.</p><p>PROCEDURES: One hundred forty-one patients referred to our department for FDG-PET/CT for suspected lung cancer were re-evaluated for atherosclerotic lesions. Cardiovascular risk factors were analyzed based on patient records.</p><p>RESULTS: Forty-two percent of the patients had three cardiovascular risk factors or more. Nine percent of all plaques were assessed as active FDG-accumulating plaques, 88% were inactive calcified plaques, and 2% were mixed. The abdominal aorta was the vessel with the highest plaque count. Patients with one risk factor had significantly less active and inactive plaques.</p><p>CONCLUSIONS: The observed association between the numbers of cardiovascular risk factors and the numbers of FDG-accumulating plaques as well as calcified plaques further supports the validity and value of FDG-PET/CT in the non-invasive identification and characterization of atherosclerotic disease.</p>}},
author = {{Wassélius, Johan A and Larsson, Stig A and Jacobsson, Hans}},
issn = {{1536-1632}},
keywords = {{Aged; Atherosclerosis; Calcinosis; Female; Fluorodeoxyglucose F18; Humans; Male; Positron-Emission Tomography; Radiopharmaceuticals; Risk Factors; Tomography, X-Ray Computed; Journal Article; Research Support, Non-U.S. Gov't}},
language = {{eng}},
month = {{05}},
number = {{6}},
pages = {{9--455}},
publisher = {{Springer}},
series = {{Molecular Imaging and Biology}},
title = {{FDG-accumulating atherosclerotic plaques identified with 18F-FDG-PET/CT in 141 patients}},
url = {{http://dx.doi.org/10.1007/s11307-009-0223-2}},
doi = {{10.1007/s11307-009-0223-2}},
volume = {{11}},
year = {{2009}},
}