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Functional activation of the frontal lobes. Regional cerebral blood flow findings in normals and in patients with frontal lobe dementia performing a word fluency test

Warkentin, Siegbert LU and Passant, Ulla LU (1993) In Dementia (Switzerland) 4(3-4). p.188-191
Abstract
The present study examined the utility of the Word Fluency Test (WFT) as a frontal-lobe-activating test in brain imaging. Regional cerebral blood flow (rCBF) was measured during rest and during the WFT in 49 healthy volunteers and in 15 patients with frontal lobe dementia (FLD). The results showed a highly significant frontal lobe activation in 85% of the normal subjects. This finding was not related to age or to the level of performance on the WFT. A significant frontal activation was seen in 13 of the 15 FLD patients. The frontal flow increase did not reach normal levels, and was not related to age, illness duration or severity of clinical symptoms. The results suggest that the WFT is an ideal test to use in conjunction with functional... (More)
The present study examined the utility of the Word Fluency Test (WFT) as a frontal-lobe-activating test in brain imaging. Regional cerebral blood flow (rCBF) was measured during rest and during the WFT in 49 healthy volunteers and in 15 patients with frontal lobe dementia (FLD). The results showed a highly significant frontal lobe activation in 85% of the normal subjects. This finding was not related to age or to the level of performance on the WFT. A significant frontal activation was seen in 13 of the 15 FLD patients. The frontal flow increase did not reach normal levels, and was not related to age, illness duration or severity of clinical symptoms. The results suggest that the WFT is an ideal test to use in conjunction with functional imaging in normals as well as in patients with organic dementia. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dementia (Switzerland)
volume
4
issue
3-4
pages
188 - 191
publisher
Karger
external identifiers
  • scopus:0027302793
ISSN
1013-7424
DOI
10.1159/000107322
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Faculty of Medicine (000022000), Department of Child and Youth Psychiatry (013303003), Clinical Memory Research Unit (013242610), Department of Psychogeriatrics (013304000)
id
59bd9b5d-94c0-4bc9-9a5d-526621e81feb (old id 1296282)
date added to LUP
2016-04-04 13:09:06
date last changed
2021-01-03 08:26:43
@article{59bd9b5d-94c0-4bc9-9a5d-526621e81feb,
  abstract     = {{The present study examined the utility of the Word Fluency Test (WFT) as a frontal-lobe-activating test in brain imaging. Regional cerebral blood flow (rCBF) was measured during rest and during the WFT in 49 healthy volunteers and in 15 patients with frontal lobe dementia (FLD). The results showed a highly significant frontal lobe activation in 85% of the normal subjects. This finding was not related to age or to the level of performance on the WFT. A significant frontal activation was seen in 13 of the 15 FLD patients. The frontal flow increase did not reach normal levels, and was not related to age, illness duration or severity of clinical symptoms. The results suggest that the WFT is an ideal test to use in conjunction with functional imaging in normals as well as in patients with organic dementia.}},
  author       = {{Warkentin, Siegbert and Passant, Ulla}},
  issn         = {{1013-7424}},
  language     = {{eng}},
  number       = {{3-4}},
  pages        = {{188--191}},
  publisher    = {{Karger}},
  series       = {{Dementia (Switzerland)}},
  title        = {{Functional activation of the frontal lobes. Regional cerebral blood flow findings in normals and in patients with frontal lobe dementia performing a word fluency test}},
  url          = {{http://dx.doi.org/10.1159/000107322}},
  doi          = {{10.1159/000107322}},
  volume       = {{4}},
  year         = {{1993}},
}