Acidaemia at Birth: Risk factors, diagnosis and prognosis, with special reference to maternal fever in labour
(1997)- Abstract
- Acidaemia at birth is a result of an impaired intrauterine gas exchange. Between 1988 and 1996, acid-base balance in cord artery blood pH was assessed in 23 016 of 27 064 newborns (85%). Obstetric risk factors for acidaemia (cord artery pH < 7.05) were identified in a case-control study. Independent risk factors were breech delivery, administration of oxytocin or pethidine, cord entanglement and male gender. In a matched-pair study, factors associated with the development of maternal fever during term labour were identified: epidural analgesia, long interval between rupture of the membranes and delivery, and long latency phase of labour. Maternal fever during term labour was associated with neonatal infectious morbidity, but not with... (More)
- Acidaemia at birth is a result of an impaired intrauterine gas exchange. Between 1988 and 1996, acid-base balance in cord artery blood pH was assessed in 23 016 of 27 064 newborns (85%). Obstetric risk factors for acidaemia (cord artery pH < 7.05) were identified in a case-control study. Independent risk factors were breech delivery, administration of oxytocin or pethidine, cord entanglement and male gender. In a matched-pair study, factors associated with the development of maternal fever during term labour were identified: epidural analgesia, long interval between rupture of the membranes and delivery, and long latency phase of labour. Maternal fever during term labour was associated with neonatal infectious morbidity, but not with newborn acidaemia.
Two regimens for fetal surveillance in low-risk labour were compared in a randomised study; continuous and intermittent electronic fetal monitoring with two-hour intervals. No significant differences were found in rates of detected abnormal fet (Less) - Abstract (Swedish)
- Popular Abstract in Swedish
Under fostertiden är fostret beroende av tillförsel av syre och näringsämnen via moderkakan och navelsträngen, och koldioxid som bildas vid dess ämnesomsätt-ning avges i motsatt riktning. Under förlossningen ökar trycket i livmodern vid varje värk, så att tillförseln av syrerikt blod från modern till moderkakan till-fälligt nedsätts. Det finns också en risk att navelsträngen tillfälligt kläms åt i samband med värkarna. Av dessa skäl innebär förlossningen en viss risksituation för barnet, som i värsta fall kan dö eller drabbas av skada till följd av syrebrist och koldioxidansamling, s.k. förlossningsasfyxi.
Dessa komplikationer var förr vanliga; 1958 dog ungefär vart hundrade... (More) - Popular Abstract in Swedish
Under fostertiden är fostret beroende av tillförsel av syre och näringsämnen via moderkakan och navelsträngen, och koldioxid som bildas vid dess ämnesomsätt-ning avges i motsatt riktning. Under förlossningen ökar trycket i livmodern vid varje värk, så att tillförseln av syrerikt blod från modern till moderkakan till-fälligt nedsätts. Det finns också en risk att navelsträngen tillfälligt kläms åt i samband med värkarna. Av dessa skäl innebär förlossningen en viss risksituation för barnet, som i värsta fall kan dö eller drabbas av skada till följd av syrebrist och koldioxidansamling, s.k. förlossningsasfyxi.
Dessa komplikationer var förr vanliga; 1958 dog ungefär vart hundrade barn i asfyxi under förlossningen. Stora ansträngningar har gjorts att nedbringa dessa komplikationer. På 1960-talet introducerades CTG (kardiotokografi) som en metod för samtidig övervakning av barnets hjärtfrekvens och livmoderns värkaktivitet. Eftersom försämrad syretillförsel eller blodtillförsel via navel-strängen indirekt (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/29325
- author
- Herbst, Andreas LU
- supervisor
- opponent
-
- Weber, Tom, Hvidovre, Denmark
- organization
- publishing date
- 1997
- type
- Thesis
- publication status
- published
- subject
- keywords
- andrology, gynaecology, Obstetrics, outcome, risk factors, perinatal asphyxia, acidosis, Acidaemia, reproduction, sexuality, Obstetrik, gynekologi, andrologi, reproduktion, sexualitet
- pages
- 160 pages
- publisher
- Department of Obstetrics and Gynecology, Lund University
- defense location
- N/A
- defense date
- 1997-06-06 10:15:00
- external identifiers
-
- other:ISRN LUMEDW/MEKL--97/1027--SE
- ISBN
- 91-628-2541-0
- language
- English
- LU publication?
- yes
- id
- 5a27aba9-b37d-4ec3-8e2b-1770c01c0266 (old id 29325)
- date added to LUP
- 2016-04-04 11:32:22
- date last changed
- 2018-11-21 21:05:31
@phdthesis{5a27aba9-b37d-4ec3-8e2b-1770c01c0266,
abstract = {{Acidaemia at birth is a result of an impaired intrauterine gas exchange. Between 1988 and 1996, acid-base balance in cord artery blood pH was assessed in 23 016 of 27 064 newborns (85%). Obstetric risk factors for acidaemia (cord artery pH < 7.05) were identified in a case-control study. Independent risk factors were breech delivery, administration of oxytocin or pethidine, cord entanglement and male gender. In a matched-pair study, factors associated with the development of maternal fever during term labour were identified: epidural analgesia, long interval between rupture of the membranes and delivery, and long latency phase of labour. Maternal fever during term labour was associated with neonatal infectious morbidity, but not with newborn acidaemia.<br/><br>
<br/><br>
Two regimens for fetal surveillance in low-risk labour were compared in a randomised study; continuous and intermittent electronic fetal monitoring with two-hour intervals. No significant differences were found in rates of detected abnormal fet}},
author = {{Herbst, Andreas}},
isbn = {{91-628-2541-0}},
keywords = {{andrology; gynaecology; Obstetrics; outcome; risk factors; perinatal asphyxia; acidosis; Acidaemia; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet}},
language = {{eng}},
publisher = {{Department of Obstetrics and Gynecology, Lund University}},
school = {{Lund University}},
title = {{Acidaemia at Birth: Risk factors, diagnosis and prognosis, with special reference to maternal fever in labour}},
year = {{1997}},
}