Occupational risk factors for small bowel carcinoid tumor: A European population-based case-control study
(2002) In Journal of Occupational and Environmental Medicine 44(6). p.516-522- Abstract
- Small bowel carcinoid tumor (SBC) is a rare disease of unknown etiology bill with all age-, sex-, and place-specific occurrence that may indicate an occupational origin. A European multicenter population-based case-control study was conducted from 1995 through 1997. Incident SBC cases between 35 and 69 years of age (n = 101) were identified, together with 3335 controls sampled from the catchment area of the cases. Histological review performed by a reference pathologist left 99 cases for study; 84 cases and 2070 population controls were interviewed. The industries most closely associated (a twofold or more odds ratio [OR]) with SBC taking into account a 10-year time lag after exposure were, among women, employment in wholesale industry of... (More)
- Small bowel carcinoid tumor (SBC) is a rare disease of unknown etiology bill with all age-, sex-, and place-specific occurrence that may indicate an occupational origin. A European multicenter population-based case-control study was conducted from 1995 through 1997. Incident SBC cases between 35 and 69 years of age (n = 101) were identified, together with 3335 controls sampled from the catchment area of the cases. Histological review performed by a reference pathologist left 99 cases for study; 84 cases and 2070 population controls were interviewed. The industries most closely associated (a twofold or more odds ratio [OR]) with SBC taking into account a 10-year time lag after exposure were, among women, employment in wholesale industry of food and beverages (OR, 8.2; 95% confidence interval [CI], [1.9 to 34.9]) and among men, manufacture of motor vehicle bodies (OR, 5.2; 95% CI, 1.2 to 22.4), footwear (OR, 3.9: 95% CI, 0.9 to 16.1), and metal structures (OR, 3.3; 95% CI, 1.0 to 10.4). The identified high-risk occupations with all OR above 2 were shoemakers, structural metal preparers, construction painters and other construction workers. bookkeepers, machine fitters, and welders (men). The OR for regular occupational use of organic. solvents for at least half a year was 2.0 (95% CI, 1.0 to 4.2). Exposure to rust-preventive paint containing lead was suggested as another potential occupational exposure (OR, 9.1; 95% CI, 0.8 to 107). This explorative study suggests an association between certain occupational exposures and SBC, bill some of these associations could be attributable to chance. All findings should be regarded as tentative. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/909846
- author
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Occupational and Environmental Medicine
- volume
- 44
- issue
- 6
- pages
- 516 - 522
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:12085477
- wos:000176267200012
- scopus:18544383955
- ISSN
- 1536-5948
- language
- English
- LU publication?
- yes
- id
- 5a3b9df9-5f93-44a9-9bbd-f8e824ab6da0 (old id 909846)
- alternative location
- http://www.joem.org/pt/re/joem/abstract.00043764-200206000-00012.htm
- date added to LUP
- 2016-04-01 16:50:18
- date last changed
- 2022-03-15 03:17:00
@article{5a3b9df9-5f93-44a9-9bbd-f8e824ab6da0, abstract = {{Small bowel carcinoid tumor (SBC) is a rare disease of unknown etiology bill with all age-, sex-, and place-specific occurrence that may indicate an occupational origin. A European multicenter population-based case-control study was conducted from 1995 through 1997. Incident SBC cases between 35 and 69 years of age (n = 101) were identified, together with 3335 controls sampled from the catchment area of the cases. Histological review performed by a reference pathologist left 99 cases for study; 84 cases and 2070 population controls were interviewed. The industries most closely associated (a twofold or more odds ratio [OR]) with SBC taking into account a 10-year time lag after exposure were, among women, employment in wholesale industry of food and beverages (OR, 8.2; 95% confidence interval [CI], [1.9 to 34.9]) and among men, manufacture of motor vehicle bodies (OR, 5.2; 95% CI, 1.2 to 22.4), footwear (OR, 3.9: 95% CI, 0.9 to 16.1), and metal structures (OR, 3.3; 95% CI, 1.0 to 10.4). The identified high-risk occupations with all OR above 2 were shoemakers, structural metal preparers, construction painters and other construction workers. bookkeepers, machine fitters, and welders (men). The OR for regular occupational use of organic. solvents for at least half a year was 2.0 (95% CI, 1.0 to 4.2). Exposure to rust-preventive paint containing lead was suggested as another potential occupational exposure (OR, 9.1; 95% CI, 0.8 to 107). This explorative study suggests an association between certain occupational exposures and SBC, bill some of these associations could be attributable to chance. All findings should be regarded as tentative.}}, author = {{Kaerlev, L and Teglbjaerg, PS and Sabroe, S and Kolstad, HA and Ahrens, W and Eriksson, Mikael and Guenel, P and Hardell, L and Cyr, D and Ballard, T and Zambon, P and Suarez-Varela, MMM and Stang, A and Olsen, J}}, issn = {{1536-5948}}, language = {{eng}}, number = {{6}}, pages = {{516--522}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Journal of Occupational and Environmental Medicine}}, title = {{Occupational risk factors for small bowel carcinoid tumor: A European population-based case-control study}}, url = {{http://www.joem.org/pt/re/joem/abstract.00043764-200206000-00012.htm}}, volume = {{44}}, year = {{2002}}, }