Periodontitis related to cardiovascular events and mortality : a long-time longitudinal study
(2021) In Clinical Oral Investigations 25(6). p.4085-4095- Abstract
Objective: The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years. Material and methods: At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered. Results: Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up... (More)
Objective: The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years. Material and methods: At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered. Results: Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60–93 years (HR: 1.5, CI: 1.1–2.1, p = 0.017), in women (HR: 2.1, CI: 1.3–3.4, p = 0.002), and in individuals 78–96 years (HR: 1.7, CI: 1.0–2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2–1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1–1.9, p = 0.006) or in ages 60–72 years (HR: 2.2, CI: 1.5–3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3–2.4, p = 0.000). Conclusions: Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death. Clinical relevance: Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.
(Less)
- author
- Bengtsson, Viveca Wallin LU ; Persson, Gösta Rutger ; Berglund, Johan Sanmartin LU and Renvert, Stefan
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Epidemiology, Ischemic heart disease, Mortality, Periodontitis
- in
- Clinical Oral Investigations
- volume
- 25
- issue
- 6
- pages
- 11 pages
- publisher
- Springer
- external identifiers
-
- scopus:85099869347
- pmid:33506429
- ISSN
- 1432-6981
- DOI
- 10.1007/s00784-020-03739-x
- language
- English
- LU publication?
- yes
- id
- 5a5c2c2e-5248-4994-b8d5-80cc18fc2da7
- date added to LUP
- 2021-12-16 15:24:05
- date last changed
- 2024-06-17 01:30:07
@article{5a5c2c2e-5248-4994-b8d5-80cc18fc2da7,
abstract = {{<p>Objective: The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years. Material and methods: At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered. Results: Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60–93 years (HR: 1.5, CI: 1.1–2.1, p = 0.017), in women (HR: 2.1, CI: 1.3–3.4, p = 0.002), and in individuals 78–96 years (HR: 1.7, CI: 1.0–2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2–1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1–1.9, p = 0.006) or in ages 60–72 years (HR: 2.2, CI: 1.5–3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3–2.4, p = 0.000). Conclusions: Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death. Clinical relevance: Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.</p>}},
author = {{Bengtsson, Viveca Wallin and Persson, Gösta Rutger and Berglund, Johan Sanmartin and Renvert, Stefan}},
issn = {{1432-6981}},
keywords = {{Epidemiology; Ischemic heart disease; Mortality; Periodontitis}},
language = {{eng}},
number = {{6}},
pages = {{4085--4095}},
publisher = {{Springer}},
series = {{Clinical Oral Investigations}},
title = {{Periodontitis related to cardiovascular events and mortality : a long-time longitudinal study}},
url = {{http://dx.doi.org/10.1007/s00784-020-03739-x}},
doi = {{10.1007/s00784-020-03739-x}},
volume = {{25}},
year = {{2021}},
}