Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain
Mattsson, Karin LU ; Johnson, Elyse V. ; Malmendal, Anders LU ; Linse, Sara LU ; Hansson, Lars Anders LU
and Cedervall, Tommy
LU
(2017)
In Scientific Reports
7(1).
- Abstract
The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour and metabolism of organisms remains elusive. Here we demonstrate that plastic nanoparticles reduce survival of aquatic zooplankton and penetrate the blood-to-brain barrier in fish and cause behavioural disorders. Hence, for the first time, we uncover direct interactions between plastic nanoparticles and brain tissue, which is the likely... (More)
The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour and metabolism of organisms remains elusive. Here we demonstrate that plastic nanoparticles reduce survival of aquatic zooplankton and penetrate the blood-to-brain barrier in fish and cause behavioural disorders. Hence, for the first time, we uncover direct interactions between plastic nanoparticles and brain tissue, which is the likely mechanism behind the observed behavioural disorders in the top consumer. In a broader perspective, our findings demonstrate that plastic nanoparticles are transferred up through a food chain, enter the brain of the top consumer and affect its behaviour, thereby severely disrupting the function of natural ecosystems.
(Less)
- author
- Mattsson, Karin
LU
; Johnson, Elyse V.
; Malmendal, Anders
LU
; Linse, Sara
LU
; Hansson, Lars Anders
LU
and Cedervall, Tommy
LU
- organization
- publishing date
- 2017-12-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scientific Reports
- volume
- 7
- issue
- 1
- article number
- 11452
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:28904346
- wos:000410666900010
- scopus:85029316282
- ISSN
- 2045-2322
- DOI
- 10.1038/s41598-017-10813-0
- language
- English
- LU publication?
- yes
- id
- 5aca1e1a-d870-4329-a1e0-d66646d868fd
- date added to LUP
- 2017-09-28 15:02:15
- date last changed
- 2025-01-07 21:12:04
@article{5aca1e1a-d870-4329-a1e0-d66646d868fd,
abstract = {{<p>The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour and metabolism of organisms remains elusive. Here we demonstrate that plastic nanoparticles reduce survival of aquatic zooplankton and penetrate the blood-to-brain barrier in fish and cause behavioural disorders. Hence, for the first time, we uncover direct interactions between plastic nanoparticles and brain tissue, which is the likely mechanism behind the observed behavioural disorders in the top consumer. In a broader perspective, our findings demonstrate that plastic nanoparticles are transferred up through a food chain, enter the brain of the top consumer and affect its behaviour, thereby severely disrupting the function of natural ecosystems.</p>}},
author = {{Mattsson, Karin and Johnson, Elyse V. and Malmendal, Anders and Linse, Sara and Hansson, Lars Anders and Cedervall, Tommy}},
issn = {{2045-2322}},
language = {{eng}},
month = {{12}},
number = {{1}},
publisher = {{Nature Publishing Group}},
series = {{Scientific Reports}},
title = {{Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain}},
url = {{http://dx.doi.org/10.1038/s41598-017-10813-0}},
doi = {{10.1038/s41598-017-10813-0}},
volume = {{7}},
year = {{2017}},
}