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Repeated polyploidization shapes divergence in floral morphology in Lithophragma bolanderi (Saxifragaceae)

Gross, Karin LU ; Yazdi, Homa Papoli LU ; Schlager, Elisabeth ; Lilley, Jodie LU ; Romero-Bravo, Andrés ; Runemark, Anna LU ; Thompson, John N. and Friberg, Magne LU (2025) In Proceedings of the National Academy of Sciences of the United States of America 122(33).
Abstract

Polyploidization is an important driver of evolution and diversification in flowering plants. Here, we assess how repeated polyploidization may have shaped diversification of floral morphology in Lithophragma bolanderi (Saxifragaceae). This species comprises multiple cytotypes and varies geographically in its interactions with specialized pollinating moths in the genus Greya (Prodoxidae). Past studies have shown that coevolution with these moths has favored particular suites of floral characters but does not fully explain local and regional floral diversification. We combined phenotypic and genomic data from more than 1,800 individuals from 40 L. bolanderi populations spread across its entire range. Flow-cytometric analyses revealed a... (More)

Polyploidization is an important driver of evolution and diversification in flowering plants. Here, we assess how repeated polyploidization may have shaped diversification of floral morphology in Lithophragma bolanderi (Saxifragaceae). This species comprises multiple cytotypes and varies geographically in its interactions with specialized pollinating moths in the genus Greya (Prodoxidae). Past studies have shown that coevolution with these moths has favored particular suites of floral characters but does not fully explain local and regional floral diversification. We combined phenotypic and genomic data from more than 1,800 individuals from 40 L. bolanderi populations spread across its entire range. Flow-cytometric analyses revealed a geographic mosaic of populations comprising one to four of three dominant (diploid, tetraploid, hexaploid) and three rare (triploid, pentaploid, octoploid) cytotypes. Whole-genome resequencing of a subset of populations suggested that polyploids arose from multiple autopolyploidization events, rather than a single event and/or through hybridization, albeit with some signals consistent with low levels of introgression from the congener Lithophragma glabrum. Quantification of flower traits from plants grown in a common garden showed that cytotype explained more than 15% of the variation in floral morphology, with polyploids showing more variability than diploids. Experimental induction of neopolyploids directly induced phenotypic changes but also indicated that local selection may have favored subsequent convergence in floral morphology among cytotypes in natural populations. Collectively, this comprehensive and integrative approach provides insights into how variability generating processes, such as polyploidization integrates with selection from species interactions to shape local floral diversification.

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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diversification, floral evolution, geographic mosaic, pollination, polyploidy
in
Proceedings of the National Academy of Sciences of the United States of America
volume
122
issue
33
article number
e2505119122
publisher
National Academy of Sciences
external identifiers
  • scopus:105013531019
  • pmid:40802687
ISSN
0027-8424
DOI
10.1073/pnas.2505119122
language
English
LU publication?
yes
id
5b02083a-b441-46ba-8899-35aa8263f62c
date added to LUP
2025-11-05 14:41:08
date last changed
2025-11-06 03:00:03
@article{5b02083a-b441-46ba-8899-35aa8263f62c,
  abstract     = {{<p>Polyploidization is an important driver of evolution and diversification in flowering plants. Here, we assess how repeated polyploidization may have shaped diversification of floral morphology in Lithophragma bolanderi (Saxifragaceae). This species comprises multiple cytotypes and varies geographically in its interactions with specialized pollinating moths in the genus Greya (Prodoxidae). Past studies have shown that coevolution with these moths has favored particular suites of floral characters but does not fully explain local and regional floral diversification. We combined phenotypic and genomic data from more than 1,800 individuals from 40 L. bolanderi populations spread across its entire range. Flow-cytometric analyses revealed a geographic mosaic of populations comprising one to four of three dominant (diploid, tetraploid, hexaploid) and three rare (triploid, pentaploid, octoploid) cytotypes. Whole-genome resequencing of a subset of populations suggested that polyploids arose from multiple autopolyploidization events, rather than a single event and/or through hybridization, albeit with some signals consistent with low levels of introgression from the congener Lithophragma glabrum. Quantification of flower traits from plants grown in a common garden showed that cytotype explained more than 15% of the variation in floral morphology, with polyploids showing more variability than diploids. Experimental induction of neopolyploids directly induced phenotypic changes but also indicated that local selection may have favored subsequent convergence in floral morphology among cytotypes in natural populations. Collectively, this comprehensive and integrative approach provides insights into how variability generating processes, such as polyploidization integrates with selection from species interactions to shape local floral diversification.</p>}},
  author       = {{Gross, Karin and Yazdi, Homa Papoli and Schlager, Elisabeth and Lilley, Jodie and Romero-Bravo, Andrés and Runemark, Anna and Thompson, John N. and Friberg, Magne}},
  issn         = {{0027-8424}},
  keywords     = {{diversification; floral evolution; geographic mosaic; pollination; polyploidy}},
  language     = {{eng}},
  number       = {{33}},
  publisher    = {{National Academy of Sciences}},
  series       = {{Proceedings of the National Academy of Sciences of the United States of America}},
  title        = {{Repeated polyploidization shapes divergence in floral morphology in Lithophragma bolanderi (Saxifragaceae)}},
  url          = {{http://dx.doi.org/10.1073/pnas.2505119122}},
  doi          = {{10.1073/pnas.2505119122}},
  volume       = {{122}},
  year         = {{2025}},
}