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Sorting biomolecules with microdevices

Chou, Chia Fu ; Austin, Robert H. ; Bakajin, Olgica ; Tegenfeldt, Jonas O. LU orcid ; Castelino, Judith A. ; Chan, Shirley S. LU ; Cox, Edward C. ; Craighead, Harold ; Darnton, Nicholas and Duke, Thomas , et al. (2000) In Electrophoresis 21(1). p.81-90
Abstract

Micro- and nanofabrication techniques have provided an unprecedented opportunity to create a designed world in which separation and fractionation technologies which normally occur on the macroscopic scale can be optimized by designing structures which utilize the basic physics of the process, or new processes can be realized by building structures which normally do not exist without external design. Since microfabrication is exceedingly sophisticated in its development, it is possible to design and construct highly creative microdevices which allow one to probe specific aspects of biological objects. We give examples of uses of micro- and nanofabrication which, as opposed to simply shrinking the size of the vessels or tubes used in... (More)

Micro- and nanofabrication techniques have provided an unprecedented opportunity to create a designed world in which separation and fractionation technologies which normally occur on the macroscopic scale can be optimized by designing structures which utilize the basic physics of the process, or new processes can be realized by building structures which normally do not exist without external design. Since microfabrication is exceedingly sophisticated in its development, it is possible to design and construct highly creative microdevices which allow one to probe specific aspects of biological objects. We give examples of uses of micro- and nanofabrication which, as opposed to simply shrinking the size of the vessels or tubes used in macroscopic lab environments, utilize our understanding of the physics of the process to take advantage of fabrication technologies.

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publishing date
type
Contribution to journal
publication status
published
keywords
Fractionation, Microfabricated arrays, Microfluidics
in
Electrophoresis
volume
21
issue
1
pages
10 pages
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:10634473
  • scopus:17444438876
ISSN
0173-0835
DOI
10.1002/(SICI)1522-2683(20000101)21:1<81::AID-ELPS81>3.0.CO;2-#
language
English
LU publication?
no
id
5b577569-7706-4bf5-8d74-d039bb93f155
date added to LUP
2018-10-20 10:46:09
date last changed
2022-01-31 06:19:36
@article{5b577569-7706-4bf5-8d74-d039bb93f155,
  abstract     = {{<p>Micro- and nanofabrication techniques have provided an unprecedented opportunity to create a designed world in which separation and fractionation technologies which normally occur on the macroscopic scale can be optimized by designing structures which utilize the basic physics of the process, or new processes can be realized by building structures which normally do not exist without external design. Since microfabrication is exceedingly sophisticated in its development, it is possible to design and construct highly creative microdevices which allow one to probe specific aspects of biological objects. We give examples of uses of micro- and nanofabrication which, as opposed to simply shrinking the size of the vessels or tubes used in macroscopic lab environments, utilize our understanding of the physics of the process to take advantage of fabrication technologies.</p>}},
  author       = {{Chou, Chia Fu and Austin, Robert H. and Bakajin, Olgica and Tegenfeldt, Jonas O. and Castelino, Judith A. and Chan, Shirley S. and Cox, Edward C. and Craighead, Harold and Darnton, Nicholas and Duke, Thomas and Han, Jongyoon and Turner, Steve}},
  issn         = {{0173-0835}},
  keywords     = {{Fractionation; Microfabricated arrays; Microfluidics}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  pages        = {{81--90}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Electrophoresis}},
  title        = {{Sorting biomolecules with microdevices}},
  url          = {{http://dx.doi.org/10.1002/(SICI)1522-2683(20000101)21:1<81::AID-ELPS81>3.0.CO;2-#}},
  doi          = {{10.1002/(SICI)1522-2683(20000101)21:1<81::AID-ELPS81>3.0.CO;2-#}},
  volume       = {{21}},
  year         = {{2000}},
}