Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients
(2020) In Research in Autism Spectrum Disorders 78.- Abstract
Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of... (More)
Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results: The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach's alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion: Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings.
(Less)
- author
- Fusar-Poli, Laura ; Bisso, Emanuele ; Concas, Ilaria ; Surace, Teresa ; Tinacci, Silvia ; Vanella, Antonio ; Furnari, Rosaria ; Signorelli, Maria Salvina ; Nylander, Lena LU and Aguglia, Eugenio
- organization
- publishing date
- 2020-10-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adult, Autism spectrum disorder, Clinician-rated tool, Differential diagnosis, Misdiagnosis, Psychiatry, Screening
- in
- Research in Autism Spectrum Disorders
- volume
- 78
- article number
- 101668
- publisher
- Elsevier
- external identifiers
-
- scopus:85090908376
- ISSN
- 1750-9467
- DOI
- 10.1016/j.rasd.2020.101668
- language
- English
- LU publication?
- yes
- id
- 5c1498b1-f7f2-41a8-9f21-2ae6dc620474
- date added to LUP
- 2020-09-30 15:14:08
- date last changed
- 2022-04-19 01:10:59
@article{5c1498b1-f7f2-41a8-9f21-2ae6dc620474, abstract = {{<p>Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results: The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach's alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion: Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings.</p>}}, author = {{Fusar-Poli, Laura and Bisso, Emanuele and Concas, Ilaria and Surace, Teresa and Tinacci, Silvia and Vanella, Antonio and Furnari, Rosaria and Signorelli, Maria Salvina and Nylander, Lena and Aguglia, Eugenio}}, issn = {{1750-9467}}, keywords = {{Adult; Autism spectrum disorder; Clinician-rated tool; Differential diagnosis; Misdiagnosis; Psychiatry; Screening}}, language = {{eng}}, month = {{10}}, publisher = {{Elsevier}}, series = {{Research in Autism Spectrum Disorders}}, title = {{Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients}}, url = {{http://dx.doi.org/10.1016/j.rasd.2020.101668}}, doi = {{10.1016/j.rasd.2020.101668}}, volume = {{78}}, year = {{2020}}, }