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Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients

Fusar-Poli, Laura ; Bisso, Emanuele ; Concas, Ilaria ; Surace, Teresa ; Tinacci, Silvia ; Vanella, Antonio ; Furnari, Rosaria ; Signorelli, Maria Salvina ; Nylander, Lena LU and Aguglia, Eugenio (2020) In Research in Autism Spectrum Disorders 78.
Abstract

Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of... (More)

Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results: The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach's alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion: Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings.

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; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Autism spectrum disorder, Clinician-rated tool, Differential diagnosis, Misdiagnosis, Psychiatry, Screening
in
Research in Autism Spectrum Disorders
volume
78
article number
101668
publisher
Elsevier
external identifiers
  • scopus:85090908376
ISSN
1750-9467
DOI
10.1016/j.rasd.2020.101668
language
English
LU publication?
yes
id
5c1498b1-f7f2-41a8-9f21-2ae6dc620474
date added to LUP
2020-09-30 15:14:08
date last changed
2022-04-19 01:10:59
@article{5c1498b1-f7f2-41a8-9f21-2ae6dc620474,
  abstract     = {{<p>Background: The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods: We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results: The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach's alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion: Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings.</p>}},
  author       = {{Fusar-Poli, Laura and Bisso, Emanuele and Concas, Ilaria and Surace, Teresa and Tinacci, Silvia and Vanella, Antonio and Furnari, Rosaria and Signorelli, Maria Salvina and Nylander, Lena and Aguglia, Eugenio}},
  issn         = {{1750-9467}},
  keywords     = {{Adult; Autism spectrum disorder; Clinician-rated tool; Differential diagnosis; Misdiagnosis; Psychiatry; Screening}},
  language     = {{eng}},
  month        = {{10}},
  publisher    = {{Elsevier}},
  series       = {{Research in Autism Spectrum Disorders}},
  title        = {{Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients}},
  url          = {{http://dx.doi.org/10.1016/j.rasd.2020.101668}},
  doi          = {{10.1016/j.rasd.2020.101668}},
  volume       = {{78}},
  year         = {{2020}},
}