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Glucagon and insulin release from the allografted canine pancreas

Brynger, H. ; Claes, G. and Lernmark LU orcid (1975) In European Surgical Research 7(3). p.170-180
Abstract

Six previously pancreatectomized dogs were transplanted with ductligated, pancreatic allografts. Glucagon and insulin levels in the venous outflow from the graft and in the systemic circulation were determined during the first 60 minutes after transplantation. Two of the dogs were subjected to L-arginine stimulation 5 days after transplantation and the glucagon levels in the venous outflow from the graft were determined. The glucagon and insulin concentrations increased rapidly after transplantation, describing a biphasic curve. In response to L-arginine stimulation, an increased glucagon release was observed.

Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
keywords
Glucagon release, Insulin release, l-Arginine stimulation, Pancreas transplantation
in
European Surgical Research
volume
7
issue
3
pages
170 - 180
publisher
Karger
external identifiers
  • scopus:0016695893
  • pmid:1098914
ISSN
0014-312X
DOI
10.1159/000127803
language
English
LU publication?
no
id
5c32b1ca-c7ad-4058-bcba-9f41b2f86715
date added to LUP
2019-09-18 12:15:01
date last changed
2025-01-09 23:13:36
@article{5c32b1ca-c7ad-4058-bcba-9f41b2f86715,
  abstract     = {{<p>Six previously pancreatectomized dogs were transplanted with ductligated, pancreatic allografts. Glucagon and insulin levels in the venous outflow from the graft and in the systemic circulation were determined during the first 60 minutes after transplantation. Two of the dogs were subjected to L-arginine stimulation 5 days after transplantation and the glucagon levels in the venous outflow from the graft were determined. The glucagon and insulin concentrations increased rapidly after transplantation, describing a biphasic curve. In response to L-arginine stimulation, an increased glucagon release was observed.</p>}},
  author       = {{Brynger, H. and Claes, G. and Lernmark}},
  issn         = {{0014-312X}},
  keywords     = {{Glucagon release; Insulin release; l-Arginine stimulation; Pancreas transplantation}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{3}},
  pages        = {{170--180}},
  publisher    = {{Karger}},
  series       = {{European Surgical Research}},
  title        = {{Glucagon and insulin release from the allografted canine pancreas}},
  url          = {{http://dx.doi.org/10.1159/000127803}},
  doi          = {{10.1159/000127803}},
  volume       = {{7}},
  year         = {{1975}},
}