Additional colloids have only a minor haemodilutive effect after surgery for aneurysmal subarachnoid haemorrhage
(1999) In British Journal of Neurosurgery 13(4). p.399-404- Abstract
- Haemodilution is commonly used as prophylaxis, as well as treatment for cerebral ischaemia after aneurysmal subarachnoid haemorrhage (SAH). Thirty-six patients operated for aneurysmal SAH were evaluated retrospectively; 24 received haemodilutive therapy and 12 patients, as a control group, received no additional therapy. There was a 'spontaneous' drop in haematocrit by 22% in both groups, and a corresponding drop in haemoglobin by 23% in the treatment group and 19% in the non-haemodiluted group, during the first 4 days after the SAH. After the initial decrease the haematocrit remained stable between 0.28 and 0.33 until day 14 in both groups. The haemodilutive group had only a minor lower haematocrit level during days 8-12 as the additional... (More)
- Haemodilution is commonly used as prophylaxis, as well as treatment for cerebral ischaemia after aneurysmal subarachnoid haemorrhage (SAH). Thirty-six patients operated for aneurysmal SAH were evaluated retrospectively; 24 received haemodilutive therapy and 12 patients, as a control group, received no additional therapy. There was a 'spontaneous' drop in haematocrit by 22% in both groups, and a corresponding drop in haemoglobin by 23% in the treatment group and 19% in the non-haemodiluted group, during the first 4 days after the SAH. After the initial decrease the haematocrit remained stable between 0.28 and 0.33 until day 14 in both groups. The haemodilutive group had only a minor lower haematocrit level during days 8-12 as the additional fluid resulted in increased renal excretion. This minor difference was, however, significant (p < 0.02). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1114908
- author
- Ekelund, A ; Säveland, Hans LU ; Reinstrup, Peter LU and Brandt, Lennart LU
- organization
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Colloids, Haemodilution, Haematocrit, Subarachnoid Haemorrhage
- in
- British Journal of Neurosurgery
- volume
- 13
- issue
- 4
- pages
- 399 - 404
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:10616568
- scopus:0032803570
- ISSN
- 0268-8697
- DOI
- 10.1080/02688699943529
- language
- English
- LU publication?
- yes
- id
- 5e063ffc-5e44-4ced-8fe2-ecddc4597f55 (old id 1114908)
- date added to LUP
- 2016-04-01 11:59:57
- date last changed
- 2022-01-26 21:22:48
@article{5e063ffc-5e44-4ced-8fe2-ecddc4597f55,
abstract = {{Haemodilution is commonly used as prophylaxis, as well as treatment for cerebral ischaemia after aneurysmal subarachnoid haemorrhage (SAH). Thirty-six patients operated for aneurysmal SAH were evaluated retrospectively; 24 received haemodilutive therapy and 12 patients, as a control group, received no additional therapy. There was a 'spontaneous' drop in haematocrit by 22% in both groups, and a corresponding drop in haemoglobin by 23% in the treatment group and 19% in the non-haemodiluted group, during the first 4 days after the SAH. After the initial decrease the haematocrit remained stable between 0.28 and 0.33 until day 14 in both groups. The haemodilutive group had only a minor lower haematocrit level during days 8-12 as the additional fluid resulted in increased renal excretion. This minor difference was, however, significant (p < 0.02).}},
author = {{Ekelund, A and Säveland, Hans and Reinstrup, Peter and Brandt, Lennart}},
issn = {{0268-8697}},
keywords = {{Colloids; Haemodilution; Haematocrit; Subarachnoid Haemorrhage}},
language = {{eng}},
number = {{4}},
pages = {{399--404}},
publisher = {{Taylor & Francis}},
series = {{British Journal of Neurosurgery}},
title = {{Additional colloids have only a minor haemodilutive effect after surgery for aneurysmal subarachnoid haemorrhage}},
url = {{http://dx.doi.org/10.1080/02688699943529}},
doi = {{10.1080/02688699943529}},
volume = {{13}},
year = {{1999}},
}