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Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits

Je, Byoung Il; Gruel, Jeremy LU ; Lee, Young Koung; Bommert, Peter; Arevalo, Edgar Demesa; Eveland, Andrea L.; Wu, Qingyu; Goldshmidt, Alexander; Meeley, Robert and Bartlett, Madelaine, et al. (2016) In Nature Genetics 48(7). p.785-791
Abstract

Shoot apical meristems are stem cell niches that balance proliferation with the incorporation of daughter cells into organ primordia. This balance is maintained by CLAVATA-WUSCHEL feedback signaling between the stem cells at the tip of the meristem and the underlying organizing center. Signals that provide feedback from organ primordia to control the stem cell niche in plants have also been hypothesized, but their identities are unknown. Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell control and responds to a CLAVATA3/ESR-related (CLE) peptide expressed in organ primordia. We modeled our results to propose a regulatory system that transmits signals from differentiating cells in organ... (More)

Shoot apical meristems are stem cell niches that balance proliferation with the incorporation of daughter cells into organ primordia. This balance is maintained by CLAVATA-WUSCHEL feedback signaling between the stem cells at the tip of the meristem and the underlying organizing center. Signals that provide feedback from organ primordia to control the stem cell niche in plants have also been hypothesized, but their identities are unknown. Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell control and responds to a CLAVATA3/ESR-related (CLE) peptide expressed in organ primordia. We modeled our results to propose a regulatory system that transmits signals from differentiating cells in organ primordia back to the stem cell niche and that appears to function broadly in the plant kingdom. Furthermore, we demonstrate an application of this new signaling feedback, by showing that weak alleles of fea3 enhance hybrid maize yield traits.

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Nature Genetics
volume
48
issue
7
pages
7 pages
publisher
Nature Publishing Group
external identifiers
  • scopus:84968546981
  • wos:000378840100016
ISSN
1061-4036
DOI
10.1038/ng.3567
language
English
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yes
id
5f13e9e1-2091-4826-a863-23b673cfbc49
date added to LUP
2017-01-25 09:39:14
date last changed
2017-10-22 05:25:32
@article{5f13e9e1-2091-4826-a863-23b673cfbc49,
  abstract     = {<p>Shoot apical meristems are stem cell niches that balance proliferation with the incorporation of daughter cells into organ primordia. This balance is maintained by CLAVATA-WUSCHEL feedback signaling between the stem cells at the tip of the meristem and the underlying organizing center. Signals that provide feedback from organ primordia to control the stem cell niche in plants have also been hypothesized, but their identities are unknown. Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell control and responds to a CLAVATA3/ESR-related (CLE) peptide expressed in organ primordia. We modeled our results to propose a regulatory system that transmits signals from differentiating cells in organ primordia back to the stem cell niche and that appears to function broadly in the plant kingdom. Furthermore, we demonstrate an application of this new signaling feedback, by showing that weak alleles of fea3 enhance hybrid maize yield traits.</p>},
  author       = {Je, Byoung Il and Gruel, Jeremy and Lee, Young Koung and Bommert, Peter and Arevalo, Edgar Demesa and Eveland, Andrea L. and Wu, Qingyu and Goldshmidt, Alexander and Meeley, Robert and Bartlett, Madelaine and Komatsu, Mai and Sakai, Hajime and Jönsson, Henrik and Jackson, David},
  issn         = {1061-4036},
  language     = {eng},
  month        = {07},
  number       = {7},
  pages        = {785--791},
  publisher    = {Nature Publishing Group},
  series       = {Nature Genetics},
  title        = {Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits},
  url          = {http://dx.doi.org/10.1038/ng.3567},
  volume       = {48},
  year         = {2016},
}