Effect of perioperative blood transfusion and cell saver on the incidence of postoperative infective complications in patients with an aneurysm of the abdominal aorta
(1992) In British Journal of Surgery 158(9). p.477-480- Abstract
OBJECTIVE: To find out if there was an association between perioperative blood transfusion and the development of infective complications, and whether the use of the cell saver for autologous transfusion had any influence.
DESIGN: Retrospective study.
SETTING: University Hospital.
SUBJECTS: 102 consecutive patients who had been operated on for aneurysms of the abdominal aorta.
MAIN OUTCOME MEASURES: Morbidity and mortality.
RESULTS: 32 of the 102 patients developed infective complications. Thirteen patients died (six after emergency and seven after elective operations). Nine died as a direct result of infection, one of intra-abdominal bleeding, one of necrosis of the colon, and two of cardiopulmonary... (More)
OBJECTIVE: To find out if there was an association between perioperative blood transfusion and the development of infective complications, and whether the use of the cell saver for autologous transfusion had any influence.
DESIGN: Retrospective study.
SETTING: University Hospital.
SUBJECTS: 102 consecutive patients who had been operated on for aneurysms of the abdominal aorta.
MAIN OUTCOME MEASURES: Morbidity and mortality.
RESULTS: 32 of the 102 patients developed infective complications. Thirteen patients died (six after emergency and seven after elective operations). Nine died as a direct result of infection, one of intra-abdominal bleeding, one of necrosis of the colon, and two of cardiopulmonary complications. The incidence of infective complications was directly related to the number of units of blood transfused, being 0 when 0 or 1 was given; 11 (20%) when 2-4 units were given; 12 (55%) when 5-8 units were given; and 9 (69%) when the number was 9 or more. The cell saver had no influence on the incidence. Other factors associated with higher rates of infective complications were the insertion of a bifurcated prosthesis (p = 0.03), and emergency operation (p < 0.001).
CONCLUSION: These results confirm the association between blood transfusion and the incidence of infective complications. It may be that more intensive use of the cell saver and preoperatively saved autologous blood could reduce the rate of infective complications.
(Less)
- author
- Verwaal, V J LU ; Wobbes, T ; Koopman-van Gemert, A W ; Buskens, F G and Theeuwes, A G
- publishing date
- 1992-09
- type
- Contribution to journal
- publication status
- published
- keywords
- Age Factors, Aortic Aneurysm, Abdominal/complications, Blood Transfusion/statistics & numerical data, Chi-Square Distribution, Humans, Incidence, Intraoperative Care/statistics & numerical data, Logistic Models, Prospective Studies, Risk Factors, Sex Factors, Surgical Wound Infection/epidemiology
- in
- British Journal of Surgery
- volume
- 158
- issue
- 9
- pages
- 477 - 480
- publisher
- Oxford University Press
- external identifiers
-
- scopus:0026779121
- pmid:1358214
- ISSN
- 1102-4151
- language
- English
- LU publication?
- no
- id
- 60554a61-cdde-48a1-9813-81b4b2c3e054
- date added to LUP
- 2022-04-12 10:55:12
- date last changed
- 2024-01-08 03:52:02
@article{60554a61-cdde-48a1-9813-81b4b2c3e054,
abstract = {{<p>OBJECTIVE: To find out if there was an association between perioperative blood transfusion and the development of infective complications, and whether the use of the cell saver for autologous transfusion had any influence.</p><p>DESIGN: Retrospective study.</p><p>SETTING: University Hospital.</p><p>SUBJECTS: 102 consecutive patients who had been operated on for aneurysms of the abdominal aorta.</p><p>MAIN OUTCOME MEASURES: Morbidity and mortality.</p><p>RESULTS: 32 of the 102 patients developed infective complications. Thirteen patients died (six after emergency and seven after elective operations). Nine died as a direct result of infection, one of intra-abdominal bleeding, one of necrosis of the colon, and two of cardiopulmonary complications. The incidence of infective complications was directly related to the number of units of blood transfused, being 0 when 0 or 1 was given; 11 (20%) when 2-4 units were given; 12 (55%) when 5-8 units were given; and 9 (69%) when the number was 9 or more. The cell saver had no influence on the incidence. Other factors associated with higher rates of infective complications were the insertion of a bifurcated prosthesis (p = 0.03), and emergency operation (p < 0.001).</p><p>CONCLUSION: These results confirm the association between blood transfusion and the incidence of infective complications. It may be that more intensive use of the cell saver and preoperatively saved autologous blood could reduce the rate of infective complications.</p>}},
author = {{Verwaal, V J and Wobbes, T and Koopman-van Gemert, A W and Buskens, F G and Theeuwes, A G}},
issn = {{1102-4151}},
keywords = {{Age Factors; Aortic Aneurysm, Abdominal/complications; Blood Transfusion/statistics & numerical data; Chi-Square Distribution; Humans; Incidence; Intraoperative Care/statistics & numerical data; Logistic Models; Prospective Studies; Risk Factors; Sex Factors; Surgical Wound Infection/epidemiology}},
language = {{eng}},
number = {{9}},
pages = {{477--480}},
publisher = {{Oxford University Press}},
series = {{British Journal of Surgery}},
title = {{Effect of perioperative blood transfusion and cell saver on the incidence of postoperative infective complications in patients with an aneurysm of the abdominal aorta}},
volume = {{158}},
year = {{1992}},
}