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Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy

Lindqvist, Pelle LU and Gudmundsson, Saemundur LU (2001) In BJOG: An International Journal of Obstetrics & Gynaecology 108(10). p.5-1103
Abstract
Abstract

To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers... (More)
Abstract

To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden. (Less)
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type
Contribution to journal
publication status
published
subject
in
BJOG: An International Journal of Obstetrics & Gynaecology
volume
108
issue
10
pages
5 - 1103
publisher
Wiley-Blackwell
external identifiers
  • scopus:0034793160
ISSN
1471-0528
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Research Unit for Urogynaecology and Reproductive Pharmacology (013242710)
id
d8e1e3af-3053-4f22-aeb1-f95fb02bffd2 (old id 608867)
alternative location
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11702845
date added to LUP
2016-04-04 13:58:57
date last changed
2022-01-30 01:12:44
@article{d8e1e3af-3053-4f22-aeb1-f95fb02bffd2,
  abstract     = {{Abstract<br/><br>
To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden.}},
  author       = {{Lindqvist, Pelle and Gudmundsson, Saemundur}},
  issn         = {{1471-0528}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{5--1103}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{BJOG: An International Journal of Obstetrics & Gynaecology}},
  title        = {{Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy}},
  url          = {{http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11702845}},
  volume       = {{108}},
  year         = {{2001}},
}