Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy
(2001) In BJOG: An International Journal of Obstetrics & Gynaecology 108(10). p.5-1103- Abstract
- Abstract
To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers... (More) - Abstract
To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/608867
- author
- Lindqvist, Pelle LU and Gudmundsson, Saemundur LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BJOG: An International Journal of Obstetrics & Gynaecology
- volume
- 108
- issue
- 10
- pages
- 5 - 1103
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0034793160
- ISSN
- 1471-0528
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Research Unit for Urogynaecology and Reproductive Pharmacology (013242710)
- id
- d8e1e3af-3053-4f22-aeb1-f95fb02bffd2 (old id 608867)
- alternative location
- http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11702845
- date added to LUP
- 2016-04-04 13:58:57
- date last changed
- 2022-01-30 01:12:44
@article{d8e1e3af-3053-4f22-aeb1-f95fb02bffd2, abstract = {{Abstract<br/><br> To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden.}}, author = {{Lindqvist, Pelle and Gudmundsson, Saemundur}}, issn = {{1471-0528}}, language = {{eng}}, number = {{10}}, pages = {{5--1103}}, publisher = {{Wiley-Blackwell}}, series = {{BJOG: An International Journal of Obstetrics & Gynaecology}}, title = {{Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy}}, url = {{http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11702845}}, volume = {{108}}, year = {{2001}}, }