Suitable test concentration of cobalt and concomitant reactivity to nickel and chromium. A multicentre study from the Swedish Contact Dermatitis Research Group
(2021) In Contact Dermatitis 84(3). p.153-158- Abstract
Background: In Sweden, cobalt chloride 0.5% has been included in the baseline series since the mid-1980s. A recent study from Stockholm showed that cobalt chloride 1% petrolatum (pet.) was more suitable than 0.5%. Cobalt chloride at 1.0% has been patch tested for decades in many European countries and around the world. Objectives: To study the suitability of patch testing to cobalt 1.0% vs 0.5% and to analyze the co-occurrence of allergy to cobalt, chromium, and nickel. Results: Contact allergy to cobalt was shown in 90 patients (6.6%). Eighty (5.9%) patients tested positive to cobalt 1.0%. Thirty-seven of the 90 patients (41.1%) with cobalt allergy were missed by cobalt 0.5% and 10 (0.7%) were missed by cobalt 1.0% (P <.001). No... (More)
Background: In Sweden, cobalt chloride 0.5% has been included in the baseline series since the mid-1980s. A recent study from Stockholm showed that cobalt chloride 1% petrolatum (pet.) was more suitable than 0.5%. Cobalt chloride at 1.0% has been patch tested for decades in many European countries and around the world. Objectives: To study the suitability of patch testing to cobalt 1.0% vs 0.5% and to analyze the co-occurrence of allergy to cobalt, chromium, and nickel. Results: Contact allergy to cobalt was shown in 90 patients (6.6%). Eighty (5.9%) patients tested positive to cobalt 1.0%. Thirty-seven of the 90 patients (41.1%) with cobalt allergy were missed by cobalt 0.5% and 10 (0.7%) were missed by cobalt 1.0% (P <.001). No case of patch test sensitization was reported. Allergy to chromium was seen in 2.6% and allergy to nickel in 13.3%. Solitary allergy to cobalt without nickel allergy was shown in 61.1% of cobalt-positive individuals. Female patients had larger proportions of positive reactions to cobalt (P =.036) and nickel (P <.001) than males. Conclusion: The results speak in favor of replacing cobalt chloride 0.5% with cobalt chloride 1.0% pet. in the Swedish baseline series, which will be done 2021.
(Less)
- author
- Isaksson, Marléne LU ; Hagvall, Lina ; Glas, Bo ; Lagrelius, Maria ; Lidén, Carola ; Matura, Mihaly ; Nyman, Gunnar ; Stenberg, Berndt ; Svedman, Cecilia LU and Bruze, Magnus LU
- organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- allergic contact dermatitis, chromium allergy, cobalt allergy, contact sensitization, delayed hypersensitivity, nickel allergy, patch testing
- in
- Contact Dermatitis
- volume
- 84
- issue
- 3
- pages
- 153 - 158
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:32996589
- scopus:85092911713
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.13710
- language
- English
- LU publication?
- yes
- id
- 60b70209-8725-4a18-a396-d2c63655806e
- date added to LUP
- 2020-11-12 09:36:16
- date last changed
- 2024-09-19 08:58:06
@article{60b70209-8725-4a18-a396-d2c63655806e, abstract = {{<p>Background: In Sweden, cobalt chloride 0.5% has been included in the baseline series since the mid-1980s. A recent study from Stockholm showed that cobalt chloride 1% petrolatum (pet.) was more suitable than 0.5%. Cobalt chloride at 1.0% has been patch tested for decades in many European countries and around the world. Objectives: To study the suitability of patch testing to cobalt 1.0% vs 0.5% and to analyze the co-occurrence of allergy to cobalt, chromium, and nickel. Results: Contact allergy to cobalt was shown in 90 patients (6.6%). Eighty (5.9%) patients tested positive to cobalt 1.0%. Thirty-seven of the 90 patients (41.1%) with cobalt allergy were missed by cobalt 0.5% and 10 (0.7%) were missed by cobalt 1.0% (P <.001). No case of patch test sensitization was reported. Allergy to chromium was seen in 2.6% and allergy to nickel in 13.3%. Solitary allergy to cobalt without nickel allergy was shown in 61.1% of cobalt-positive individuals. Female patients had larger proportions of positive reactions to cobalt (P =.036) and nickel (P <.001) than males. Conclusion: The results speak in favor of replacing cobalt chloride 0.5% with cobalt chloride 1.0% pet. in the Swedish baseline series, which will be done 2021.</p>}}, author = {{Isaksson, Marléne and Hagvall, Lina and Glas, Bo and Lagrelius, Maria and Lidén, Carola and Matura, Mihaly and Nyman, Gunnar and Stenberg, Berndt and Svedman, Cecilia and Bruze, Magnus}}, issn = {{0105-1873}}, keywords = {{allergic contact dermatitis; chromium allergy; cobalt allergy; contact sensitization; delayed hypersensitivity; nickel allergy; patch testing}}, language = {{eng}}, number = {{3}}, pages = {{153--158}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Suitable test concentration of cobalt and concomitant reactivity to nickel and chromium. A multicentre study from the Swedish Contact Dermatitis Research Group}}, url = {{http://dx.doi.org/10.1111/cod.13710}}, doi = {{10.1111/cod.13710}}, volume = {{84}}, year = {{2021}}, }