Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants
Lund, Anna My LU ; Löfqvist, Chatarina ; Pivodic, Aldina ; Lundgren, Pia ; Hård, Anna Lena ; Hellström, Ann LU and Hansen-Pupp, Ingrid LU
(2020)
In Acta Paediatrica, International Journal of Paediatrics
109(6).
p.1138-1147
- Abstract
Aim: Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants. Methods: Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days. Results: Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z-scores for weight, length and head circumference at 28 postnatal days and at... (More)
Aim: Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants. Methods: Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days. Results: Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z-scores for weight, length and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z-score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z-scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (mL/kg/d). Conclusion: Unpasteurised MM was positively associated with longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.
(Less)
- author
- Lund, Anna My
LU
; Löfqvist, Chatarina
; Pivodic, Aldina
; Lundgren, Pia
; Hård, Anna Lena
; Hellström, Ann
LU
and Hansen-Pupp, Ingrid
LU
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- donor milk, growth, maternal milk, pasteurisation, preterm
- in
- Acta Paediatrica, International Journal of Paediatrics
- volume
- 109
- issue
- 6
- pages
- 10 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85076363845
- pmid:31747093
- ISSN
- 0803-5253
- DOI
- 10.1111/apa.15102
- language
- English
- LU publication?
- yes
- id
- 613602ff-cff3-41f2-bee5-7fba23da5874
- date added to LUP
- 2021-01-12 10:39:53
- date last changed
- 2024-05-03 00:17:48
@article{613602ff-cff3-41f2-bee5-7fba23da5874,
abstract = {{<p>Aim: Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants. Methods: Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days. Results: Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z-scores for weight, length and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z-score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z-scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (mL/kg/d). Conclusion: Unpasteurised MM was positively associated with longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.</p>}},
author = {{Lund, Anna My and Löfqvist, Chatarina and Pivodic, Aldina and Lundgren, Pia and Hård, Anna Lena and Hellström, Ann and Hansen-Pupp, Ingrid}},
issn = {{0803-5253}},
keywords = {{donor milk; growth; maternal milk; pasteurisation; preterm}},
language = {{eng}},
number = {{6}},
pages = {{1138--1147}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Paediatrica, International Journal of Paediatrics}},
title = {{Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants}},
url = {{http://dx.doi.org/10.1111/apa.15102}},
doi = {{10.1111/apa.15102}},
volume = {{109}},
year = {{2020}},
}