Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat
(2014) In Indian Journal of Biochemistry and Biophysics 51(5). p.365-371- Abstract
Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric parameters and oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3 groups (n = 8): G1 = control; G2 = rats exposed to dietary restriction of 30%; and G3 = rats exposed to dietary restriction of 60%. Energy restriction decreased final body weight, oxidation of carbohydrates and lipid, oxygen consumption (VO2), carbon dioxide production (VCO2), resting metabolic rate (RMR), but elevated respiratory quotient (RQ). G3 animals also displayed an imbalance in the oxidant/antioxidant system, as... (More)
Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric parameters and oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3 groups (n = 8): G1 = control; G2 = rats exposed to dietary restriction of 30%; and G3 = rats exposed to dietary restriction of 60%. Energy restriction decreased final body weight, oxidation of carbohydrates and lipid, oxygen consumption (VO2), carbon dioxide production (VCO2), resting metabolic rate (RMR), but elevated respiratory quotient (RQ). G3 animals also displayed an imbalance in the oxidant/antioxidant system, as revealed by the decrease in the lipid hydroperoxide (LH) level and GSH-Px activity in heart tissue. In conclusion, dietary restriction decreased oxidative metabolism, as seen by the colorimetric profiles and controlled oxidative stress in cardiac tissue.
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- author
- Kawahara, Elisa Ito ; Maués, N. H.P.B. ; dos Santos, Klinsmann Carolo LU ; Barbanera, Pedro Octávio ; Braga, Camila Pereira and Fernandes, Ana Angélica Henrique
- publishing date
- 2014-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Calorimetry, Energy restriction, Myocardium, Nutritional parameters, Oxidative stress
- in
- Indian Journal of Biochemistry and Biophysics
- volume
- 51
- issue
- 5
- pages
- 7 pages
- publisher
- National Institute of Science Communication and Information Resources (NISCAIR)
- external identifiers
-
- pmid:25630106
- scopus:84909947309
- ISSN
- 0301-1208
- language
- English
- LU publication?
- no
- id
- 624df931-7914-49b4-9d5c-0a145d787b19
- alternative location
- http://nopr.niscair.res.in/bitstream/123456789/29885/1/IJBB%2051%285%29%20365-371.pdf
- date added to LUP
- 2019-03-28 15:14:53
- date last changed
- 2024-04-30 03:25:19
@article{624df931-7914-49b4-9d5c-0a145d787b19,
abstract = {{<p>Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric parameters and oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3 groups (n = 8): G1 = control; G2 = rats exposed to dietary restriction of 30%; and G3 = rats exposed to dietary restriction of 60%. Energy restriction decreased final body weight, oxidation of carbohydrates and lipid, oxygen consumption (VO2), carbon dioxide production (VCO2), resting metabolic rate (RMR), but elevated respiratory quotient (RQ). G3 animals also displayed an imbalance in the oxidant/antioxidant system, as revealed by the decrease in the lipid hydroperoxide (LH) level and GSH-Px activity in heart tissue. In conclusion, dietary restriction decreased oxidative metabolism, as seen by the colorimetric profiles and controlled oxidative stress in cardiac tissue.</p>}},
author = {{Kawahara, Elisa Ito and Maués, N. H.P.B. and dos Santos, Klinsmann Carolo and Barbanera, Pedro Octávio and Braga, Camila Pereira and Fernandes, Ana Angélica Henrique}},
issn = {{0301-1208}},
keywords = {{Calorimetry; Energy restriction; Myocardium; Nutritional parameters; Oxidative stress}},
language = {{eng}},
month = {{01}},
number = {{5}},
pages = {{365--371}},
publisher = {{National Institute of Science Communication and Information Resources (NISCAIR)}},
series = {{Indian Journal of Biochemistry and Biophysics}},
title = {{Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat}},
url = {{http://nopr.niscair.res.in/bitstream/123456789/29885/1/IJBB%2051%285%29%20365-371.pdf}},
volume = {{51}},
year = {{2014}},
}