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Estimating the distribution of the G2 phase duration from flow cytometric histograms

Larsson Lönn, Sara LU ; Rydén, Tobias LU ; Holst, Ulla LU ; Oredsson, Stina LU and Johansson, Maria C LU (2008) In Mathematical Biosciences 211(1). p.1-17
Abstract
A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S phase duration and the estimated means and standard deviations of the G2 phase duration are all in the same range.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cell cycle progression, Branching process, G2 phase duration, Flow cytometry
in
Mathematical Biosciences
volume
211
issue
1
pages
1 - 17
publisher
Elsevier
external identifiers
  • wos:000253029900001
  • scopus:37349005841
ISSN
0025-5564
DOI
10.1016/j.mbs.2007.08.009
language
English
LU publication?
yes
id
4a1483b0-70af-4f14-a674-9b9b2d22aec1 (old id 632608)
date added to LUP
2007-11-29 13:41:31
date last changed
2017-01-01 05:57:07
@article{4a1483b0-70af-4f14-a674-9b9b2d22aec1,
  abstract     = {A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S phase duration and the estimated means and standard deviations of the G2 phase duration are all in the same range.},
  author       = {Larsson Lönn, Sara and Rydén, Tobias and Holst, Ulla and Oredsson, Stina and Johansson, Maria C},
  issn         = {0025-5564},
  keyword      = {Cell cycle progression,Branching process,G2 phase duration,Flow cytometry},
  language     = {eng},
  number       = {1},
  pages        = {1--17},
  publisher    = {Elsevier},
  series       = {Mathematical Biosciences},
  title        = {Estimating the distribution of the G2 phase duration from flow cytometric histograms},
  url          = {http://dx.doi.org/10.1016/j.mbs.2007.08.009},
  volume       = {211},
  year         = {2008},
}