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[An optical circulation amplification type biological chip detecting process]

Xie, Bin LU ; Liang, Zhenpu and Xie, Weihong (2004) CN1485617A
Abstract
The invention discloses an optical circulation enlarged type biological chip detecting method, wherein the enzyme recirculation and bioluminescence are combined, for realizing the FMNH#-[2] accumulation through the circulation on the electrodes by the NADH/NAD#+[+] oxidation-reduction, the high level accumulation FMNH#-[2] reacts with other light-emitting bottom luciferase, long chain aldehydes and oxygen, giving off fluorescent light having wavelength of 490nm. The invention realizes high sensibility, low cost and simplicity of operation, thus is suitable for each types of biological sample analysis.
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inventor
LU ; Liang, Zhenpu and Xie, Weihong
organization
alternative title
An optical circulation amplification type biological chip detecting process
publishing date
type
Patent
publication status
published
subject
patent number
CN1485617A
language
Chinese (Simplified)
LU publication?
yes
id
633b7afb-59b9-4adb-b8bd-e936ef1093e3
alternative location
https://patentimages.storage.googleapis.com/50/9b/8b/fe5a7eb0f540c0/CN1485617A.pdf
date added to LUP
2021-10-27 17:32:21
date last changed
2021-11-15 11:58:27
@misc{633b7afb-59b9-4adb-b8bd-e936ef1093e3,
  abstract     = {{The invention discloses an optical circulation enlarged type biological chip detecting method, wherein the enzyme recirculation and bioluminescence are combined, for realizing the FMNH#-[2] accumulation through the circulation on the electrodes by the NADH/NAD#+[+] oxidation-reduction, the high level accumulation FMNH#-[2] reacts with other light-emitting bottom luciferase, long chain aldehydes and oxygen, giving off fluorescent light having wavelength of 490nm. The invention realizes high sensibility, low cost and simplicity of operation, thus is suitable for each types of biological sample analysis.}},
  author       = {{Xie, Bin and Liang, Zhenpu and Xie, Weihong}},
  language     = {{chi}},
  note         = {{Patent, Patent Number: CN1485617A}},
  title        = {{[An optical circulation amplification type biological chip detecting process]}},
  url          = {{https://patentimages.storage.googleapis.com/50/9b/8b/fe5a7eb0f540c0/CN1485617A.pdf}},
  year         = {{2004}},
}