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Hip prosthetic loosening : A very personal review

Mjöberg, Bengt LU orcid (2021) In World journal of orthopedics 12(9). p.629-639
Abstract

Hip prosthetic loosening is often difficult to detect at an early stage, and there has been uncertainty for a long time as to when the loosening occurs and thus to the basic causes. By comparing different diagnostic methods, we found that loosening is best defined as prosthetic migration and measured by radiostereometric analysis. Convincing evidence indicates that poor interlock, poor bone quality, and resorption of a necrotic bone bed may initiate loosening during or shortly after surgery; this forms the basis of the theory of early loosening. Biomechanical factors do affect the subsequent progression of loosening, which may increase subclinically during a long period of time. Eventually, the loosening may be detected on standard... (More)

Hip prosthetic loosening is often difficult to detect at an early stage, and there has been uncertainty for a long time as to when the loosening occurs and thus to the basic causes. By comparing different diagnostic methods, we found that loosening is best defined as prosthetic migration and measured by radiostereometric analysis. Convincing evidence indicates that poor interlock, poor bone quality, and resorption of a necrotic bone bed may initiate loosening during or shortly after surgery; this forms the basis of the theory of early loosening. Biomechanical factors do affect the subsequent progression of loosening, which may increase subclinically during a long period of time. Eventually, the loosening may be detected on standard radiographs and may be interpreted as late loosening but should to be interpreted as late detection of loosening. The theory of early loosening explains the rapid early migration, the development of periprosthetic osteolysis and granulomas, the causality between wear and loosening, and largely the epidemiology of clinical failure of hip prostheses. Aspects discussed are definition of loosening, the pattern of early migration, the choice of migration threshold, the current understanding of loosening, a less exothermic bone cement, cemented taper-slip stems, a new exciting computed tomography-based technique for simpler implant migration studies, and research suggestions.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Bone cements, Bone resorption, Hip prosthesis, Prosthesis failure, Radionuclide imaging, Radiostereometric analysis
in
World journal of orthopedics
volume
12
issue
9
pages
11 pages
publisher
Baishideng Publishing Group
external identifiers
  • pmid:34631447
  • scopus:85115241175
ISSN
2218-5836
DOI
10.5312/wjo.v12.i9.629
language
English
LU publication?
yes
id
636bc782-e055-49dc-bb5c-272b71d54c82
date added to LUP
2021-10-11 15:57:24
date last changed
2024-06-15 17:56:46
@article{636bc782-e055-49dc-bb5c-272b71d54c82,
  abstract     = {{<p>Hip prosthetic loosening is often difficult to detect at an early stage, and there has been uncertainty for a long time as to when the loosening occurs and thus to the basic causes. By comparing different diagnostic methods, we found that loosening is best defined as prosthetic migration and measured by radiostereometric analysis. Convincing evidence indicates that poor interlock, poor bone quality, and resorption of a necrotic bone bed may initiate loosening during or shortly after surgery; this forms the basis of the theory of early loosening. Biomechanical factors do affect the subsequent progression of loosening, which may increase subclinically during a long period of time. Eventually, the loosening may be detected on standard radiographs and may be interpreted as late loosening but should to be interpreted as late detection of loosening. The theory of early loosening explains the rapid early migration, the development of periprosthetic osteolysis and granulomas, the causality between wear and loosening, and largely the epidemiology of clinical failure of hip prostheses. Aspects discussed are definition of loosening, the pattern of early migration, the choice of migration threshold, the current understanding of loosening, a less exothermic bone cement, cemented taper-slip stems, a new exciting computed tomography-based technique for simpler implant migration studies, and research suggestions.</p>}},
  author       = {{Mjöberg, Bengt}},
  issn         = {{2218-5836}},
  keywords     = {{Bone cements; Bone resorption; Hip prosthesis; Prosthesis failure; Radionuclide imaging; Radiostereometric analysis}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{629--639}},
  publisher    = {{Baishideng Publishing Group}},
  series       = {{World journal of orthopedics}},
  title        = {{Hip prosthetic loosening : A very personal review}},
  url          = {{http://dx.doi.org/10.5312/wjo.v12.i9.629}},
  doi          = {{10.5312/wjo.v12.i9.629}},
  volume       = {{12}},
  year         = {{2021}},
}