An ecological study of chronic kidney disease in five Mesoamerican countries : associations with crop and heat
(2021) In BMC Public Health 21(1).- Abstract
BACKGROUND: Mesoamerica is severely affected by an epidemic of Chronic Kidney Disease of non-traditional origin (CKDnt), an epidemic with a marked variation within countries. We sought to describe the spatial distribution of CKDnt in Mesoamerica and examine area-level crop and climate risk factors.
METHODS: CKD mortality or hospital admissions data was available for five countries: Mexico, Guatemala, El Salvador, Nicaragua and Costa Rica and linked to demographic, crop and climate data. Maps were developed using Bayesian spatial regression models. Regression models were used to analyze the association between area-level CKD burden and heat and cultivation of four crops: sugarcane, banana, rice and coffee.
RESULTS: There are... (More)
BACKGROUND: Mesoamerica is severely affected by an epidemic of Chronic Kidney Disease of non-traditional origin (CKDnt), an epidemic with a marked variation within countries. We sought to describe the spatial distribution of CKDnt in Mesoamerica and examine area-level crop and climate risk factors.
METHODS: CKD mortality or hospital admissions data was available for five countries: Mexico, Guatemala, El Salvador, Nicaragua and Costa Rica and linked to demographic, crop and climate data. Maps were developed using Bayesian spatial regression models. Regression models were used to analyze the association between area-level CKD burden and heat and cultivation of four crops: sugarcane, banana, rice and coffee.
RESULTS: There are regions within each of the five countries with elevated CKD burden. Municipalities in hot areas and much sugarcane cultivation had higher CKD burden, both compared to equally hot municipalities with lower intensity of sugarcane cultivation and to less hot areas with equally intense sugarcane cultivation, but associations with other crops at different intensity and heat levels were not consistent across countries.
CONCLUSION: Mapping routinely collected, already available data could be a first step to identify areas with high CKD burden. The finding of higher CKD burden in hot regions with intense sugarcane cultivation which was repeated in all five countries agree with individual-level studies identifying heavy physical labor in heat as a key CKDnt risk factor. In contrast, no associations between CKD burden and other crops were observed.
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- author
- Hansson, Erik LU ; Mansourian, Ali LU ; Farnaghi, Mahdi LU ; Petzold, Max and Jakobsson, Kristina LU
- organization
- publishing date
- 2021-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Chronic Kidney Disease of unknown origin (CKDu), Mesoamerican countries, Associations with crop and heat, Ecological study
- in
- BMC Public Health
- volume
- 21
- issue
- 1
- article number
- 840
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:33933045
- scopus:85105209915
- ISSN
- 1471-2458
- DOI
- 10.1186/s12889-021-10822-9
- language
- English
- LU publication?
- yes
- id
- 636f17a6-1c97-4d1f-a893-0c16eb1caf89
- date added to LUP
- 2021-05-05 11:43:41
- date last changed
- 2024-06-15 10:51:17
@article{636f17a6-1c97-4d1f-a893-0c16eb1caf89,
abstract = {{<p>BACKGROUND: Mesoamerica is severely affected by an epidemic of Chronic Kidney Disease of non-traditional origin (CKDnt), an epidemic with a marked variation within countries. We sought to describe the spatial distribution of CKDnt in Mesoamerica and examine area-level crop and climate risk factors.</p><p>METHODS: CKD mortality or hospital admissions data was available for five countries: Mexico, Guatemala, El Salvador, Nicaragua and Costa Rica and linked to demographic, crop and climate data. Maps were developed using Bayesian spatial regression models. Regression models were used to analyze the association between area-level CKD burden and heat and cultivation of four crops: sugarcane, banana, rice and coffee.</p><p>RESULTS: There are regions within each of the five countries with elevated CKD burden. Municipalities in hot areas and much sugarcane cultivation had higher CKD burden, both compared to equally hot municipalities with lower intensity of sugarcane cultivation and to less hot areas with equally intense sugarcane cultivation, but associations with other crops at different intensity and heat levels were not consistent across countries.</p><p>CONCLUSION: Mapping routinely collected, already available data could be a first step to identify areas with high CKD burden. The finding of higher CKD burden in hot regions with intense sugarcane cultivation which was repeated in all five countries agree with individual-level studies identifying heavy physical labor in heat as a key CKDnt risk factor. In contrast, no associations between CKD burden and other crops were observed.</p>}},
author = {{Hansson, Erik and Mansourian, Ali and Farnaghi, Mahdi and Petzold, Max and Jakobsson, Kristina}},
issn = {{1471-2458}},
keywords = {{Chronic Kidney Disease of unknown origin (CKDu); Mesoamerican countries; Associations with crop and heat; Ecological study}},
language = {{eng}},
month = {{05}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Public Health}},
title = {{An ecological study of chronic kidney disease in five Mesoamerican countries : associations with crop and heat}},
url = {{http://dx.doi.org/10.1186/s12889-021-10822-9}},
doi = {{10.1186/s12889-021-10822-9}},
volume = {{21}},
year = {{2021}},
}