Strain-Release Driven Cycloadditions for Rapid Construction of Functionalized Pyridines and Amino Alcohols
Clementson, Sebastian LU
; Radaelli, Alessio
; Fjelbye, Kasper
; Tanner, David
and Jessing, Mikkel
(2019)
In Organic Letters
21(12).
p.4763-4766
- Abstract
- This paper describes the development of a new variant of stereoselective
strain-release driven reactions (formal homo [3 + 2] dipolar
cycloadditions) which utilize housane (1) to construct
functionalized amino alcohols and pyridine-substituted cyclopentanes in
two to three steps from simple and easily available building blocks
(nitrones and pyridine N-oxides respectively).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/63d4cadc-2694-41e5-becd-b327654402b7
- author
- Clementson, Sebastian
LU
; Radaelli, Alessio
; Fjelbye, Kasper
; Tanner, David
and Jessing, Mikkel
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- in
- Organic Letters
- volume
- 21
- issue
- 12
- pages
- 4 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- scopus:85067447525
- ISSN
- 1523-7052
- DOI
- 10.1021/acs.orglett.9b01652
- language
- English
- LU publication?
- no
- additional info
- PMID: 31180685
- id
- 63d4cadc-2694-41e5-becd-b327654402b7
- date added to LUP
- 2025-08-06 19:41:18
- date last changed
- 2025-09-01 11:17:00
@article{63d4cadc-2694-41e5-becd-b327654402b7,
abstract = {{This paper describes the development of a new variant of stereoselective<br>
strain-release driven reactions (formal homo [3 + 2] dipolar <br>
cycloadditions) which utilize housane (1) to construct <br>
functionalized amino alcohols and pyridine-substituted cyclopentanes in <br>
two to three steps from simple and easily available building blocks <br>
(nitrones and pyridine <i>N</i>-oxides respectively).}},
author = {{Clementson, Sebastian and Radaelli, Alessio and Fjelbye, Kasper and Tanner, David and Jessing, Mikkel}},
issn = {{1523-7052}},
language = {{eng}},
number = {{12}},
pages = {{4763--4766}},
publisher = {{The American Chemical Society (ACS)}},
series = {{Organic Letters}},
title = {{Strain-Release Driven Cycloadditions for Rapid Construction of Functionalized Pyridines and Amino Alcohols}},
url = {{http://dx.doi.org/10.1021/acs.orglett.9b01652}},
doi = {{10.1021/acs.orglett.9b01652}},
volume = {{21}},
year = {{2019}},
}