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Grating-based X-ray dark-field imaging : a new paradigm in radiography

Yaroshenko, Andre ; Hellbach, Katharina ; Bech, Martin LU ; Grandl, Susanne ; Reiser, Maximilian F. ; Pfeiffer, Franz and Meinel, Felix G. (2014) In Current Radiology Reports 2. p.1-9
Abstract

Grating-based X-ray dark-field contrast is an emerging new imaging modality that is demonstrating particularly high potential for radiography. The signal in dark-field X-ray imaging is determined by small-angle X-ray scattering at structures typically below the spatial resolution of the imaging setup. Thus, this technique not only yields complementary information but also visualizes information that lies under the resolution limit for conventional, absorption-based radiography. Grating-based X-ray dark-field imaging has been shown to be feasible with both synchrotron radiation and conventional X-ray tubes. Lung, breast, and bone imaging have been identified as the applications promising the main impact, but other applications are on the... (More)

Grating-based X-ray dark-field contrast is an emerging new imaging modality that is demonstrating particularly high potential for radiography. The signal in dark-field X-ray imaging is determined by small-angle X-ray scattering at structures typically below the spatial resolution of the imaging setup. Thus, this technique not only yields complementary information but also visualizes information that lies under the resolution limit for conventional, absorption-based radiography. Grating-based X-ray dark-field imaging has been shown to be feasible with both synchrotron radiation and conventional X-ray tubes. Lung, breast, and bone imaging have been identified as the applications promising the main impact, but other applications are on the horizon. Specifically, dark-field radiography has been used to detect pulmonary emphysema and assesses its regional distribution in mice and holds promise to improve the visualization of micro-calcifications in mammography and yields information about bone microstructure. Further technical developments are required to make the technique suitable for clinical use.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Grating interferometry, Lung imaging, Grating-based imaging, Pulmonary emphysema, X-ray dark-field imaging, X-ray phase-contrast imaging
in
Current Radiology Reports
volume
2
article number
57
pages
1 - 9
publisher
Springer US
external identifiers
  • scopus:84928468272
DOI
10.1007/s40134-014-0057-9
language
English
LU publication?
yes
id
641f202f-6a25-4725-9267-d61bd40ebed4
date added to LUP
2019-08-12 14:50:35
date last changed
2020-07-29 05:58:36
@article{641f202f-6a25-4725-9267-d61bd40ebed4,
  abstract     = {<p>Grating-based X-ray dark-field contrast is an emerging new imaging modality that is demonstrating particularly high potential for radiography. The signal in dark-field X-ray imaging is determined by small-angle X-ray scattering at structures typically below the spatial resolution of the imaging setup. Thus, this technique not only yields complementary information but also visualizes information that lies under the resolution limit for conventional, absorption-based radiography. Grating-based X-ray dark-field imaging has been shown to be feasible with both synchrotron radiation and conventional X-ray tubes. Lung, breast, and bone imaging have been identified as the applications promising the main impact, but other applications are on the horizon. Specifically, dark-field radiography has been used to detect pulmonary emphysema and assesses its regional distribution in mice and holds promise to improve the visualization of micro-calcifications in mammography and yields information about bone microstructure. Further technical developments are required to make the technique suitable for clinical use.</p>},
  author       = {Yaroshenko, Andre and Hellbach, Katharina and Bech, Martin and Grandl, Susanne and Reiser, Maximilian F. and Pfeiffer, Franz and Meinel, Felix G.},
  language     = {eng},
  month        = {07},
  pages        = {1--9},
  publisher    = {Springer US},
  series       = {Current Radiology Reports},
  title        = {Grating-based X-ray dark-field imaging : a new paradigm in radiography},
  url          = {http://dx.doi.org/10.1007/s40134-014-0057-9},
  doi          = {10.1007/s40134-014-0057-9},
  volume       = {2},
  year         = {2014},
}