Systematic review of the healthcare cost of bronchopulmonary dysplasia
(2021) In BMJ Open 11(8).- Abstract
To determine the costs directly or indirectly related to bronchopulmonary dysplasia (BPD) in preterm infants. The secondary objective was to stratify the costs based on gestational age and/or birth weight. Systematic literature review. PubMed and Scopus were searched on 3 February 2020. Studies were selected based on eligibility criteria by two independent reviewers. Included studies were further searched to identify eligible references and citations. Two independent reviewers extracted data with a prespecified data extraction sheet, including items from a published checklist for quality assessment. The costs in the included studies are reported descriptively. Costs of BPD. The 13 included studies reported the total costs or marginal... (More)
To determine the costs directly or indirectly related to bronchopulmonary dysplasia (BPD) in preterm infants. The secondary objective was to stratify the costs based on gestational age and/or birth weight. Systematic literature review. PubMed and Scopus were searched on 3 February 2020. Studies were selected based on eligibility criteria by two independent reviewers. Included studies were further searched to identify eligible references and citations. Two independent reviewers extracted data with a prespecified data extraction sheet, including items from a published checklist for quality assessment. The costs in the included studies are reported descriptively. Costs of BPD. The 13 included studies reported the total costs or marginal costs of BPD. Most studies reported costs during birth hospitalisation (cost range: Int$21 392–Int$1 094 509 per child, equivalent to €19 103–€977 397, in 2019) and/or during the first year of life. One study reported costs during the first 2 years; two other studies reported costs later, during the preschool period and one study included a long-term follow-up. The highest mean costs were associated with infants born at extremely low gestational ages. The quality assessment indicated a low risk of bias in the reported findings of included studies. This study was the first systematic review of costs associated with BPD. We confirmed previous reports of high costs and described the long-term follow-up necessary for preterm infants with BPD, particularly infants of very low gestational age. Moreover, we identified a need for studies that estimate costs outside hospitals and after the first year of life. CRD42020173234.
(Less)
- author
- Humayun, Jhangir ; Löfqvist, Chatarina ; Ley, David LU ; Hellström, Ann and Gyllensten, Hanna
- organization
- publishing date
- 2021-08-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- chronic airways disease, health economics, paediatric thoracic medicine, paediatrics, respiratory medicine (see thoracic medicine)
- in
- BMJ Open
- volume
- 11
- issue
- 8
- article number
- e045729
- publisher
- BMJ Publishing Group
- external identifiers
-
- scopus:85112748671
- pmid:34376441
- ISSN
- 2044-6055
- DOI
- 10.1136/bmjopen-2020-045729
- language
- English
- LU publication?
- yes
- id
- 64387e3d-7a4d-43ac-9130-c19eb175c63d
- date added to LUP
- 2021-09-14 13:05:02
- date last changed
- 2024-03-08 17:26:39
@article{64387e3d-7a4d-43ac-9130-c19eb175c63d, abstract = {{<p>To determine the costs directly or indirectly related to bronchopulmonary dysplasia (BPD) in preterm infants. The secondary objective was to stratify the costs based on gestational age and/or birth weight. Systematic literature review. PubMed and Scopus were searched on 3 February 2020. Studies were selected based on eligibility criteria by two independent reviewers. Included studies were further searched to identify eligible references and citations. Two independent reviewers extracted data with a prespecified data extraction sheet, including items from a published checklist for quality assessment. The costs in the included studies are reported descriptively. Costs of BPD. The 13 included studies reported the total costs or marginal costs of BPD. Most studies reported costs during birth hospitalisation (cost range: Int$21 392–Int$1 094 509 per child, equivalent to €19 103–€977 397, in 2019) and/or during the first year of life. One study reported costs during the first 2 years; two other studies reported costs later, during the preschool period and one study included a long-term follow-up. The highest mean costs were associated with infants born at extremely low gestational ages. The quality assessment indicated a low risk of bias in the reported findings of included studies. This study was the first systematic review of costs associated with BPD. We confirmed previous reports of high costs and described the long-term follow-up necessary for preterm infants with BPD, particularly infants of very low gestational age. Moreover, we identified a need for studies that estimate costs outside hospitals and after the first year of life. CRD42020173234.</p>}}, author = {{Humayun, Jhangir and Löfqvist, Chatarina and Ley, David and Hellström, Ann and Gyllensten, Hanna}}, issn = {{2044-6055}}, keywords = {{chronic airways disease; health economics; paediatric thoracic medicine; paediatrics; respiratory medicine (see thoracic medicine)}}, language = {{eng}}, month = {{08}}, number = {{8}}, publisher = {{BMJ Publishing Group}}, series = {{BMJ Open}}, title = {{Systematic review of the healthcare cost of bronchopulmonary dysplasia}}, url = {{http://dx.doi.org/10.1136/bmjopen-2020-045729}}, doi = {{10.1136/bmjopen-2020-045729}}, volume = {{11}}, year = {{2021}}, }