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Solvent exchange using hollow fiber prior to separation and determination of some antioxidants by high performance liquid chromatography

Farajzadeh, Mir Ali and Jönsson, Jan Åke LU (2007) In Analytica Chimica Acta 594(1). p.75-80
Abstract
This study presents a simple and rapid solvent exchange procedure using a hollow fiber. Antioxidants (Irganox 1010, Irganox 1076 and Irgafos 168) and solvents such as tetrahydrofuran (THF), carbon tetrachloride and toluene were selected as model compounds and sample solvents, respectively. After injection of the sample solution into the hollow fiber and solvent evaporation, the precipitated analytes in lumen and pores of the fiber were washed with methanol (the mobile phase for separation and determination by HPLC-diode array detection) and good chromatographic peaks were obtained. The effect of different parameters such as fiber length, volumes of sample and washing solvents were investigated and the optimum conditions were selected. The... (More)
This study presents a simple and rapid solvent exchange procedure using a hollow fiber. Antioxidants (Irganox 1010, Irganox 1076 and Irgafos 168) and solvents such as tetrahydrofuran (THF), carbon tetrachloride and toluene were selected as model compounds and sample solvents, respectively. After injection of the sample solution into the hollow fiber and solvent evaporation, the precipitated analytes in lumen and pores of the fiber were washed with methanol (the mobile phase for separation and determination by HPLC-diode array detection) and good chromatographic peaks were obtained. The effect of different parameters such as fiber length, volumes of sample and washing solvents were investigated and the optimum conditions were selected. The repeatability of the method was tested and it was found that the relative standard deviation (R.S.D.) was less than 10% for all analytes. Also enrichment factors of 3.03, 2.21 and 1.19 times were obtained for Irganox 1010, Irganox 1076 and Irgafos 168, respectively, when 200 mu L sample and 50 mu L methanol (washing solvent) were used. (c) 2007 Elsevier BX All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
chromatography, high performance liquid, antioxidants, hollow fiber, solvent exchange
in
Analytica Chimica Acta
volume
594
issue
1
pages
75 - 80
publisher
Elsevier
external identifiers
  • wos:000247506900011
  • scopus:34249890554
ISSN
1873-4324
DOI
10.1016/j.aca.2007.05.014
language
English
LU publication?
yes
id
644dba75-746d-4c27-8de9-7cecc284c234 (old id 647878)
date added to LUP
2007-12-11 14:01:08
date last changed
2017-01-01 07:19:42
@article{644dba75-746d-4c27-8de9-7cecc284c234,
  abstract     = {This study presents a simple and rapid solvent exchange procedure using a hollow fiber. Antioxidants (Irganox 1010, Irganox 1076 and Irgafos 168) and solvents such as tetrahydrofuran (THF), carbon tetrachloride and toluene were selected as model compounds and sample solvents, respectively. After injection of the sample solution into the hollow fiber and solvent evaporation, the precipitated analytes in lumen and pores of the fiber were washed with methanol (the mobile phase for separation and determination by HPLC-diode array detection) and good chromatographic peaks were obtained. The effect of different parameters such as fiber length, volumes of sample and washing solvents were investigated and the optimum conditions were selected. The repeatability of the method was tested and it was found that the relative standard deviation (R.S.D.) was less than 10% for all analytes. Also enrichment factors of 3.03, 2.21 and 1.19 times were obtained for Irganox 1010, Irganox 1076 and Irgafos 168, respectively, when 200 mu L sample and 50 mu L methanol (washing solvent) were used. (c) 2007 Elsevier BX All rights reserved.},
  author       = {Farajzadeh, Mir Ali and Jönsson, Jan Åke},
  issn         = {1873-4324},
  keyword      = {chromatography,high performance liquid,antioxidants,hollow fiber,solvent exchange},
  language     = {eng},
  number       = {1},
  pages        = {75--80},
  publisher    = {Elsevier},
  series       = {Analytica Chimica Acta},
  title        = {Solvent exchange using hollow fiber prior to separation and determination of some antioxidants by high performance liquid chromatography},
  url          = {http://dx.doi.org/10.1016/j.aca.2007.05.014},
  volume       = {594},
  year         = {2007},
}