Advanced

On the follicular pathway of percutaneous uptake of nanoparticles: Ion microscopy and autoradiography studies

Lekki, J. ; Stachura, Z. ; Dabros, W. ; Stachura, J. ; Menzel, F. ; Reinert, T. ; Butz, T. ; Pallon, Jan LU ; Gontier, E. and Ynsa, M. D. , et al. (2007) In Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 260(1). p.174-177
Abstract
We report on the visualization of the penetration of sunscreen formulations containing TiO2 nanoparticles (about 20 nm primary particle size) into hair follicles of both human and porcine skin using the complementary methods of ion microscopy (PIXE, RBS, STIM) and autoradiography. Particles were found as deep as approx. 400 pin in the follicle, obviously introduced mechanically rather than by a diffusive process. No particles were observed in vital tissue nor in sebaceous glands. (c) 2007 Elsevier B.V. All rights reserved.
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and , et al. (More)
; ; ; ; ; ; ; ; ; ; ; ; and (Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ion microprobe, skin penetration, titanium dioxide, nanoparticles, autoradiography
in
Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms
volume
260
issue
1
pages
174 - 177
publisher
Elsevier
external identifiers
  • wos:000248264900034
  • scopus:34250027287
ISSN
0168-583X
DOI
10.1016/j.nimb.2007.02.021
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Nuclear Physics (Faculty of Technology) (011013007)
id
7b5b92ed-1eee-44a9-b956-4940938ab773 (old id 648004)
date added to LUP
2016-04-01 16:47:44
date last changed
2020-09-23 05:27:41
@article{7b5b92ed-1eee-44a9-b956-4940938ab773,
  abstract     = {We report on the visualization of the penetration of sunscreen formulations containing TiO2 nanoparticles (about 20 nm primary particle size) into hair follicles of both human and porcine skin using the complementary methods of ion microscopy (PIXE, RBS, STIM) and autoradiography. Particles were found as deep as approx. 400 pin in the follicle, obviously introduced mechanically rather than by a diffusive process. No particles were observed in vital tissue nor in sebaceous glands. (c) 2007 Elsevier B.V. All rights reserved.},
  author       = {Lekki, J. and Stachura, Z. and Dabros, W. and Stachura, J. and Menzel, F. and Reinert, T. and Butz, T. and Pallon, Jan and Gontier, E. and Ynsa, M. D. and Moretto, P. and Kertesz, Z. and Szikszai, Z. and Kiss, A. Z.},
  issn         = {0168-583X},
  language     = {eng},
  number       = {1},
  pages        = {174--177},
  publisher    = {Elsevier},
  series       = {Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms},
  title        = {On the follicular pathway of percutaneous uptake of nanoparticles: Ion microscopy and autoradiography studies},
  url          = {http://dx.doi.org/10.1016/j.nimb.2007.02.021},
  doi          = {10.1016/j.nimb.2007.02.021},
  volume       = {260},
  year         = {2007},
}