Effects of ejaculation-to-analysis delay on levels of markers of epididymal and accessory sex gland functions and sperm motility
(2007) In Journal of Andrology 28(6). p.847-852- Abstract
- This study aimed to examine the association between the interval from ejaculation to analysis and epididymal and accessory sex gland function in relation to sperm motility. Ejaculates from 1079 men assessed for infertility were analyzed according to World Health Organization guidelines. Biochemical markers were measured in semen to assess the function of the epididymi;s (neutral alpha-glucosidase [NAG]), prostate (prostate-specific antigen [PSA] and zinc), and seminal vesicles (fructose). Three groups were defined according to time from ejaculation to analysis: G <= 30 (24 -30 minutes), G(31-60) (31-60 minutes), and G(>60) (63-80 minutes). The proportion of progressively motile sperm was significantly lower in G(>60) than in... (More)
- This study aimed to examine the association between the interval from ejaculation to analysis and epididymal and accessory sex gland function in relation to sperm motility. Ejaculates from 1079 men assessed for infertility were analyzed according to World Health Organization guidelines. Biochemical markers were measured in semen to assess the function of the epididymi;s (neutral alpha-glucosidase [NAG]), prostate (prostate-specific antigen [PSA] and zinc), and seminal vesicles (fructose). Three groups were defined according to time from ejaculation to analysis: G <= 30 (24 -30 minutes), G(31-60) (31-60 minutes), and G(>60) (63-80 minutes). The proportion of progressively motile sperm was significantly lower in G(>60) than in G(<= 30) (mean difference, 8.0%; 95% confidence interval [CI], 2.0%-13%) or G(31-60) (mean difference, 6.0%; 95% CI, 1.0%-12%). The proportion of rapid progressive sperm motility was significantly higher in G(<= 30) compared with G(31-60) (mean difference, 3.0%; 95% CI, 1.0%-5.0%) and 6160 (mean difference, 6.0%; 95% 3.0%; 95% 1.0%-10%). Sperm morphology and viability did not vary significantly between the groups. However, PSA levels in G(>60) were 29% and 31% significantly lower than in G(<= 30) (95% CI, 3.0%-54%) and G(31-60) (95% CI, 7.0%-58%), respectively. Moreover, men in G(>60) had 29% and 17% significantly lower zinc compared with those in G(<= 30) (95% CI, 4.0%-69%) and G(31-60) (95% CI, 4.0%-64%), respectively. Levels of NAG and fructose did not differ significantly between the groups. There were negative associations between the ejaculation-to-analysis interval and sperm motility and levels of PSA and zinc. In male infertility assessments, semen analysis should be performed within 60 minutes of ejaculation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/654017
- author
- Elzanaty, Saad LU and Malm, Johan LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- viability, biochemical markers, morphology, semen analysis
- in
- Journal of Andrology
- volume
- 28
- issue
- 6
- pages
- 847 - 852
- publisher
- American Society of Andrology
- external identifiers
-
- wos:000250564100009
- scopus:35848967606
- ISSN
- 0196-3635
- DOI
- 10.2164/jandrol.107.002659
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Clinical Chemistry, Malmö (013016000)
- id
- 7f723ea4-08b6-4fbe-9e8b-502a25c8de44 (old id 654017)
- date added to LUP
- 2016-04-01 16:36:30
- date last changed
- 2022-02-27 22:23:21
@article{7f723ea4-08b6-4fbe-9e8b-502a25c8de44, abstract = {{This study aimed to examine the association between the interval from ejaculation to analysis and epididymal and accessory sex gland function in relation to sperm motility. Ejaculates from 1079 men assessed for infertility were analyzed according to World Health Organization guidelines. Biochemical markers were measured in semen to assess the function of the epididymi;s (neutral alpha-glucosidase [NAG]), prostate (prostate-specific antigen [PSA] and zinc), and seminal vesicles (fructose). Three groups were defined according to time from ejaculation to analysis: G <= 30 (24 -30 minutes), G(31-60) (31-60 minutes), and G(>60) (63-80 minutes). The proportion of progressively motile sperm was significantly lower in G(>60) than in G(<= 30) (mean difference, 8.0%; 95% confidence interval [CI], 2.0%-13%) or G(31-60) (mean difference, 6.0%; 95% CI, 1.0%-12%). The proportion of rapid progressive sperm motility was significantly higher in G(<= 30) compared with G(31-60) (mean difference, 3.0%; 95% CI, 1.0%-5.0%) and 6160 (mean difference, 6.0%; 95% 3.0%; 95% 1.0%-10%). Sperm morphology and viability did not vary significantly between the groups. However, PSA levels in G(>60) were 29% and 31% significantly lower than in G(<= 30) (95% CI, 3.0%-54%) and G(31-60) (95% CI, 7.0%-58%), respectively. Moreover, men in G(>60) had 29% and 17% significantly lower zinc compared with those in G(<= 30) (95% CI, 4.0%-69%) and G(31-60) (95% CI, 4.0%-64%), respectively. Levels of NAG and fructose did not differ significantly between the groups. There were negative associations between the ejaculation-to-analysis interval and sperm motility and levels of PSA and zinc. In male infertility assessments, semen analysis should be performed within 60 minutes of ejaculation.}}, author = {{Elzanaty, Saad and Malm, Johan}}, issn = {{0196-3635}}, keywords = {{viability; biochemical markers; morphology; semen analysis}}, language = {{eng}}, number = {{6}}, pages = {{847--852}}, publisher = {{American Society of Andrology}}, series = {{Journal of Andrology}}, title = {{Effects of ejaculation-to-analysis delay on levels of markers of epididymal and accessory sex gland functions and sperm motility}}, url = {{http://dx.doi.org/10.2164/jandrol.107.002659}}, doi = {{10.2164/jandrol.107.002659}}, volume = {{28}}, year = {{2007}}, }