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Dopamine neuron systems in the brain: an update

Björklund, Anders LU and Dunnett, Stephen B. (2007) In Trends in Neurosciences 30(5). p.194-202
Abstract
The basic organization of the catecholamine-containing neuronal systems and their axonal projections in the brain was initially worked out using classical histofluorescence techniques during the 1960s and 1970s. The introduction of more versatile immunohistochemical methods, along with a range of highly sensitive tract-tracing techniques, has provided a progressively more detailed picture, making the dopamine system one of the best known, and most completely mapped, neurotransmitter systems in the brain. The purpose of the present review is to summarize our current knowledge of the diversity and neurochemical features of the nine dopamine-containing neuronal cell groups in the mammalian brain, their distinctive cellular properties, and... (More)
The basic organization of the catecholamine-containing neuronal systems and their axonal projections in the brain was initially worked out using classical histofluorescence techniques during the 1960s and 1970s. The introduction of more versatile immunohistochemical methods, along with a range of highly sensitive tract-tracing techniques, has provided a progressively more detailed picture, making the dopamine system one of the best known, and most completely mapped, neurotransmitter systems in the brain. The purpose of the present review is to summarize our current knowledge of the diversity and neurochemical features of the nine dopamine-containing neuronal cell groups in the mammalian brain, their distinctive cellular properties, and their ability to regulate their dopaminergic transmitter machinery in response to altered functional demands and aging. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Trends in Neurosciences
volume
30
issue
5
pages
194 - 202
publisher
Elsevier
external identifiers
  • wos:000246752000003
  • scopus:34247469020
ISSN
1878-108X
DOI
10.1016/j.tins.2007.03.006
language
English
LU publication?
yes
id
dc946f2d-abed-4b7d-bc2d-d480b964e12d (old id 657607)
date added to LUP
2007-12-10 14:27:54
date last changed
2017-11-19 04:03:33
@article{dc946f2d-abed-4b7d-bc2d-d480b964e12d,
  abstract     = {The basic organization of the catecholamine-containing neuronal systems and their axonal projections in the brain was initially worked out using classical histofluorescence techniques during the 1960s and 1970s. The introduction of more versatile immunohistochemical methods, along with a range of highly sensitive tract-tracing techniques, has provided a progressively more detailed picture, making the dopamine system one of the best known, and most completely mapped, neurotransmitter systems in the brain. The purpose of the present review is to summarize our current knowledge of the diversity and neurochemical features of the nine dopamine-containing neuronal cell groups in the mammalian brain, their distinctive cellular properties, and their ability to regulate their dopaminergic transmitter machinery in response to altered functional demands and aging.},
  author       = {Björklund, Anders and Dunnett, Stephen B.},
  issn         = {1878-108X},
  language     = {eng},
  number       = {5},
  pages        = {194--202},
  publisher    = {Elsevier},
  series       = {Trends in Neurosciences},
  title        = {Dopamine neuron systems in the brain: an update},
  url          = {http://dx.doi.org/10.1016/j.tins.2007.03.006},
  volume       = {30},
  year         = {2007},
}