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Unexpected sensitization routes and general frequency of contact allergies in an elderly stented Swedish population

Svedman, Cecilia LU ; Ekqvist, Susanne LU ; Möller, Halvor LU ; Björk, Jonas LU ; Gruvberger, Birgitta LU ; Holmstrom, Eva and Bruze, Magnus LU (2007) In Contact Dermatitis 56(6). p.338-343
Abstract
Contact allergy to stent material has been proposed to be a risk factor for restenosis, after percutaneous transluminal coronary angioplasty (PTCA) and stenting. Information on the general frequency of contact allergy in the elderly population is scarce and knowledge of possible sensitization routes is important to investigate. The aim of this study was to investigate contact allergy to stent materials and other allergens. Here we report our findings on the frequency of contact allergies apart from those from stent material. In this retrospective study, we patch tested an elderly population, treated with PTCA and stented, with our standard series. A dermatitis population served as controls. We found a high frequency of contact allergy in... (More)
Contact allergy to stent material has been proposed to be a risk factor for restenosis, after percutaneous transluminal coronary angioplasty (PTCA) and stenting. Information on the general frequency of contact allergy in the elderly population is scarce and knowledge of possible sensitization routes is important to investigate. The aim of this study was to investigate contact allergy to stent materials and other allergens. Here we report our findings on the frequency of contact allergies apart from those from stent material. In this retrospective study, we patch tested an elderly population, treated with PTCA and stented, with our standard series. A dermatitis population served as controls. We found a high frequency of contact allergy in both groups but a greater 'contact allergy burden', with generally higher frequencies for contact allergens, in the dermatitis patients as expected. Myroxylon pereirae and caine mix were apart from metals exceptions with statistically significant higher frequencies (P < 0.01) for the stented patients. Contact allergy to nonmetal sensitizers is common in an elderly Swedish stent population although, on the whole, substantially less than in an age and sex-matched dermatitis population. The findings indicate the importance of the oral mucosa for sensitization. In a general population that has been treated with a special medication/treatment procedure, contact allergies not suspected (such as to M. pereirae and to the metals) might suddenly peak. This underlines the importance of a careful evaluation of new products and routines with regard to contact allergies in the population. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
contact allergy, Myroxylon pereirae, elderly, stent, dental restoration
in
Contact Dermatitis
volume
56
issue
6
pages
338 - 343
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000246695000006
  • scopus:34250620842
ISSN
0105-1873
DOI
10.1111/j.1600-0536.2007.01119.x
language
English
LU publication?
yes
id
2aada864-a308-4332-b11d-b6e0b6a8fcbb (old id 657892)
date added to LUP
2007-12-18 15:37:58
date last changed
2017-08-20 03:28:13
@article{2aada864-a308-4332-b11d-b6e0b6a8fcbb,
  abstract     = {Contact allergy to stent material has been proposed to be a risk factor for restenosis, after percutaneous transluminal coronary angioplasty (PTCA) and stenting. Information on the general frequency of contact allergy in the elderly population is scarce and knowledge of possible sensitization routes is important to investigate. The aim of this study was to investigate contact allergy to stent materials and other allergens. Here we report our findings on the frequency of contact allergies apart from those from stent material. In this retrospective study, we patch tested an elderly population, treated with PTCA and stented, with our standard series. A dermatitis population served as controls. We found a high frequency of contact allergy in both groups but a greater 'contact allergy burden', with generally higher frequencies for contact allergens, in the dermatitis patients as expected. Myroxylon pereirae and caine mix were apart from metals exceptions with statistically significant higher frequencies (P &lt; 0.01) for the stented patients. Contact allergy to nonmetal sensitizers is common in an elderly Swedish stent population although, on the whole, substantially less than in an age and sex-matched dermatitis population. The findings indicate the importance of the oral mucosa for sensitization. In a general population that has been treated with a special medication/treatment procedure, contact allergies not suspected (such as to M. pereirae and to the metals) might suddenly peak. This underlines the importance of a careful evaluation of new products and routines with regard to contact allergies in the population.},
  author       = {Svedman, Cecilia and Ekqvist, Susanne and Möller, Halvor and Björk, Jonas and Gruvberger, Birgitta and Holmstrom, Eva and Bruze, Magnus},
  issn         = {0105-1873},
  keyword      = {contact allergy,Myroxylon pereirae,elderly,stent,dental restoration},
  language     = {eng},
  number       = {6},
  pages        = {338--343},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {Unexpected sensitization routes and general frequency of contact allergies in an elderly stented Swedish population},
  url          = {http://dx.doi.org/10.1111/j.1600-0536.2007.01119.x},
  volume       = {56},
  year         = {2007},
}