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Galvanically induced asymmetric optokinetic after-nystagmus

Brantberg, K and Magnusson, Måns LU (1990) In Acta oto-laryngologica 110(3-4). p.95-189
Abstract

The effect of an asymmetric vestibular input on the symmetry of horizontal optokinetic after-nystagmus (OKAN) was studied in twenty healthy subjects. Optokinetic nystagmus (OKN) was elicited by a whole-field optokinetic drug, rotating at 90 degrees/s, and eye-movements were recorded by a DC electro-oculographic technique (EOG). The ratio of OKAN following right and left-beating OKN respectively was computed. An asymmetric vestibular input was generated by a continuous bi-polar, bi-aural galvanic stimulus (1 mA) to the vestibular nerves during the optokinetic stimulation and the recording of the OKAN. During galvanic stimulation the relation between left and right-beating OKAN was asymmetric, compared with the OKAN found after... (More)

The effect of an asymmetric vestibular input on the symmetry of horizontal optokinetic after-nystagmus (OKAN) was studied in twenty healthy subjects. Optokinetic nystagmus (OKN) was elicited by a whole-field optokinetic drug, rotating at 90 degrees/s, and eye-movements were recorded by a DC electro-oculographic technique (EOG). The ratio of OKAN following right and left-beating OKN respectively was computed. An asymmetric vestibular input was generated by a continuous bi-polar, bi-aural galvanic stimulus (1 mA) to the vestibular nerves during the optokinetic stimulation and the recording of the OKAN. During galvanic stimulation the relation between left and right-beating OKAN was asymmetric, compared with the OKAN found after optokinetic stimulation only. The galvanic stimulus caused a preponderance for OKAN with the fast phase beating toward the cathode. Thus, the small vestibular asymmetry induced by the galvanic stimulus, which was not strong enough to produce nystagmus by itself, caused an asymmetric OKAN. These findings suggest that examination of OKAN may be of value to detect small vestibular asymmetries in peripheral vestibular disorders in man.

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Contribution to journal
publication status
published
subject
keywords
Adult, Electric Stimulation, Electrooculography, Female, Humans, Male, Middle Aged, Nystagmus, Physiologic, Vestibular Nerve, Journal Article, Research Support, Non-U.S. Gov't
in
Acta oto-laryngologica
volume
110
issue
3-4
pages
95 - 189
publisher
Taylor & Francis
external identifiers
  • scopus:0025180363
ISSN
0001-6489
language
English
LU publication?
yes
id
6592daf4-296f-49dc-b8bd-a7454783e4dd
date added to LUP
2017-05-03 12:44:59
date last changed
2017-05-07 04:53:03
@article{6592daf4-296f-49dc-b8bd-a7454783e4dd,
  abstract     = {<p>The effect of an asymmetric vestibular input on the symmetry of horizontal optokinetic after-nystagmus (OKAN) was studied in twenty healthy subjects. Optokinetic nystagmus (OKN) was elicited by a whole-field optokinetic drug, rotating at 90 degrees/s, and eye-movements were recorded by a DC electro-oculographic technique (EOG). The ratio of OKAN following right and left-beating OKN respectively was computed. An asymmetric vestibular input was generated by a continuous bi-polar, bi-aural galvanic stimulus (1 mA) to the vestibular nerves during the optokinetic stimulation and the recording of the OKAN. During galvanic stimulation the relation between left and right-beating OKAN was asymmetric, compared with the OKAN found after optokinetic stimulation only. The galvanic stimulus caused a preponderance for OKAN with the fast phase beating toward the cathode. Thus, the small vestibular asymmetry induced by the galvanic stimulus, which was not strong enough to produce nystagmus by itself, caused an asymmetric OKAN. These findings suggest that examination of OKAN may be of value to detect small vestibular asymmetries in peripheral vestibular disorders in man.</p>},
  author       = {Brantberg, K and Magnusson, Måns},
  issn         = {0001-6489},
  keyword      = {Adult,Electric Stimulation,Electrooculography,Female,Humans,Male,Middle Aged,Nystagmus, Physiologic,Vestibular Nerve,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  month        = {09},
  number       = {3-4},
  pages        = {95--189},
  publisher    = {Taylor & Francis},
  series       = {Acta oto-laryngologica},
  title        = {Galvanically induced asymmetric optokinetic after-nystagmus},
  volume       = {110},
  year         = {1990},
}