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Strategies to improve clinical research in surgery through international collaboration

Soreide, Kjetil ; Alderson, Derek ; Bergenfelz, Anders LU ; Beynon, John ; Connor, Saxon ; Deckelbaum, Dan L. ; Dejong, Cornelis H. ; Earnshaw, Jonathan J. ; Kyamanywa, Patrick and Perez, Rodrigo O. , et al. (2013) In The Lancet 382(9898). p.1140-1151
Abstract
More than 235 million patients undergo surgery every year worldwide, but less than 1% are enrolled in surgical clinical trials-few of which are international collaborations. Several levels of action are needed to improve this situation. International research collaborations in surgery between developed and developing countries could encourage capacity building and quality improvement, and mutually enhance care for patients with surgical disorders. Low-income and middle-income countries increasingly report much the same range of surgical diseases as do high-income countries (eg, cancer, cardiovascular disease, and the surgical sequelae of metabolic syndrome); collaboration is therefore of mutual interest. Large multinational trials that... (More)
More than 235 million patients undergo surgery every year worldwide, but less than 1% are enrolled in surgical clinical trials-few of which are international collaborations. Several levels of action are needed to improve this situation. International research collaborations in surgery between developed and developing countries could encourage capacity building and quality improvement, and mutually enhance care for patients with surgical disorders. Low-income and middle-income countries increasingly report much the same range of surgical diseases as do high-income countries (eg, cancer, cardiovascular disease, and the surgical sequelae of metabolic syndrome); collaboration is therefore of mutual interest. Large multinational trials that cross cultures and levels of socioeconomic development might have faster results and wider applicability than do single-country trials. Surgeons educated in research methods, and aided by research networks and trial centres, are needed to foster these international collaborations. Barriers to collaboration could be overcome by adoption of global strategies for regulation, health insurance, ethical approval, and indemnity coverage for doctors. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Lancet
volume
382
issue
9898
pages
1140 - 1151
publisher
Elsevier
external identifiers
  • wos:000325208100030
  • scopus:84884648125
ISSN
1474-547X
DOI
10.1016/S0140-6736(13)61455-5
language
English
LU publication?
yes
id
6621dc9c-1b33-4332-b1ad-0c7b64292e8c (old id 4172140)
date added to LUP
2016-04-01 10:24:48
date last changed
2022-03-19 20:32:05
@article{6621dc9c-1b33-4332-b1ad-0c7b64292e8c,
  abstract     = {{More than 235 million patients undergo surgery every year worldwide, but less than 1% are enrolled in surgical clinical trials-few of which are international collaborations. Several levels of action are needed to improve this situation. International research collaborations in surgery between developed and developing countries could encourage capacity building and quality improvement, and mutually enhance care for patients with surgical disorders. Low-income and middle-income countries increasingly report much the same range of surgical diseases as do high-income countries (eg, cancer, cardiovascular disease, and the surgical sequelae of metabolic syndrome); collaboration is therefore of mutual interest. Large multinational trials that cross cultures and levels of socioeconomic development might have faster results and wider applicability than do single-country trials. Surgeons educated in research methods, and aided by research networks and trial centres, are needed to foster these international collaborations. Barriers to collaboration could be overcome by adoption of global strategies for regulation, health insurance, ethical approval, and indemnity coverage for doctors.}},
  author       = {{Soreide, Kjetil and Alderson, Derek and Bergenfelz, Anders and Beynon, John and Connor, Saxon and Deckelbaum, Dan L. and Dejong, Cornelis H. and Earnshaw, Jonathan J. and Kyamanywa, Patrick and Perez, Rodrigo O. and Sakai, Yoshiharu and Winter, Desmond C.}},
  issn         = {{1474-547X}},
  language     = {{eng}},
  number       = {{9898}},
  pages        = {{1140--1151}},
  publisher    = {{Elsevier}},
  series       = {{The Lancet}},
  title        = {{Strategies to improve clinical research in surgery through international collaboration}},
  url          = {{http://dx.doi.org/10.1016/S0140-6736(13)61455-5}},
  doi          = {{10.1016/S0140-6736(13)61455-5}},
  volume       = {{382}},
  year         = {{2013}},
}