Prenatal ultrasound detection of cleft lip, or cleft palate, or both, in southern Sweden, 2006-2010.
Berggren, Helena ; Hansson, Emma LU ; Uvemark, Annika ; Svensson, Henry LU ; Sladkevicius, Povilas LU
and Becker, Magnus
LU
(2012)
In Journal of Plastic Surgery and Hand Surgery
46(2).
p.69-74
- Abstract
- It has been possible to detect cleft lip (CL), with or without cleft palate (CLP), using ultrasound (US) since the beginning of the 1980s. The aim of this study was to assess the accuracy of prenatal diagnosis of cleft lip with or without cleft palate, and isolated cleft palate (ICP), in our catchment area. Screening protocols in the different US clinics in southern Sweden were also compared, as regards evaluation of the fetal face and prenatal diagnosis of CLP. Forty-four (31%) of the patients were diagnosed by prenatal US and 97/144 (67%) were diagnosed at birth. The detection rate was 44/102 (43%) if the ICP are excluded. The specificity was 100%. Among the prenatally diagnosed clefts, 25/44 (57%) were diagnosed before the gestational... (More)
- It has been possible to detect cleft lip (CL), with or without cleft palate (CLP), using ultrasound (US) since the beginning of the 1980s. The aim of this study was to assess the accuracy of prenatal diagnosis of cleft lip with or without cleft palate, and isolated cleft palate (ICP), in our catchment area. Screening protocols in the different US clinics in southern Sweden were also compared, as regards evaluation of the fetal face and prenatal diagnosis of CLP. Forty-four (31%) of the patients were diagnosed by prenatal US and 97/144 (67%) were diagnosed at birth. The detection rate was 44/102 (43%) if the ICP are excluded. The specificity was 100%. Among the prenatally diagnosed clefts, 25/44 (57%) were diagnosed before the gestational age of 20 weeks. In 19/44 (43%) of the cases the US diagnosis of cleft was accurate in the light of the postnatal outcome. All US departments in our catchment area follow the Swedish guidelines and offer one routine US examination during the second trimester between 18 and 20 weeks of pregnancy. In addition, many of the clinics offer an additional US examination during the third trimester. Our detection rate is similar to previous findings. The detection rates and the accuracy of the prenatal diagnosis can be improved. To achieve this, an increased focus on detecting clefts, standardising scanning plans, and rescans in case of incomplete facial views, are essential. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2519892
- author
- Berggren, Helena
; Hansson, Emma
LU
; Uvemark, Annika
; Svensson, Henry
LU
; Sladkevicius, Povilas
LU
and Becker, Magnus
LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Plastic Surgery and Hand Surgery
- volume
- 46
- issue
- 2
- pages
- 69 - 74
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000302369100003
- pmid:22471252
- scopus:84859311980
- ISSN
- 2000-656X
- DOI
- 10.3109/2000656X.2012.668773
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Reconstructive Surgery (013240300), Obstetric, Gynaecological and Prenatal Ultrasound Research Unit (013242720), Surgery Research Unit (013242220)
- id
- 667aa04e-128d-44ba-9162-99f9dcb49f2b (old id 2519892)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22471252?dopt=Abstract
- date added to LUP
- 2016-04-01 10:36:38
- date last changed
- 2023-11-10 01:04:45
@article{667aa04e-128d-44ba-9162-99f9dcb49f2b,
abstract = {{It has been possible to detect cleft lip (CL), with or without cleft palate (CLP), using ultrasound (US) since the beginning of the 1980s. The aim of this study was to assess the accuracy of prenatal diagnosis of cleft lip with or without cleft palate, and isolated cleft palate (ICP), in our catchment area. Screening protocols in the different US clinics in southern Sweden were also compared, as regards evaluation of the fetal face and prenatal diagnosis of CLP. Forty-four (31%) of the patients were diagnosed by prenatal US and 97/144 (67%) were diagnosed at birth. The detection rate was 44/102 (43%) if the ICP are excluded. The specificity was 100%. Among the prenatally diagnosed clefts, 25/44 (57%) were diagnosed before the gestational age of 20 weeks. In 19/44 (43%) of the cases the US diagnosis of cleft was accurate in the light of the postnatal outcome. All US departments in our catchment area follow the Swedish guidelines and offer one routine US examination during the second trimester between 18 and 20 weeks of pregnancy. In addition, many of the clinics offer an additional US examination during the third trimester. Our detection rate is similar to previous findings. The detection rates and the accuracy of the prenatal diagnosis can be improved. To achieve this, an increased focus on detecting clefts, standardising scanning plans, and rescans in case of incomplete facial views, are essential.}},
author = {{Berggren, Helena and Hansson, Emma and Uvemark, Annika and Svensson, Henry and Sladkevicius, Povilas and Becker, Magnus}},
issn = {{2000-656X}},
language = {{eng}},
number = {{2}},
pages = {{69--74}},
publisher = {{Taylor & Francis}},
series = {{Journal of Plastic Surgery and Hand Surgery}},
title = {{Prenatal ultrasound detection of cleft lip, or cleft palate, or both, in southern Sweden, 2006-2010.}},
url = {{http://dx.doi.org/10.3109/2000656X.2012.668773}},
doi = {{10.3109/2000656X.2012.668773}},
volume = {{46}},
year = {{2012}},
}