Capsaicin enhances allergic contact dermatitis in guinea pig.
(1991) In Contact Dermatitis 24(1). p.30-34- Abstract
- Guinea pigs were sensitized to dinitrochlorobenzene (DNCB) by the intracutaneous route and challenged epicutaneously tin the flanks. The intensity of the allergic contact dermatitis was evaluated by inspection and palpation as well us by wet weight determination. With the purpose of diminishing tissue neuropeptides, and substance P in particular, the animals were treated with capsaicin either between induction and challenge, or before sensitization, In comparison with controls, the contact dermatitis was Enhanced in both groups of animals treated with capsaicin.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/66fc0f06-9341-49c1-879a-8068bc015dca
- author
- Wallengren, Joanna LU ; Ekman, Rolf and Möller, Halvor LU
- organization
- publishing date
- 1991
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Contact Dermatitis
- volume
- 24
- issue
- 1
- pages
- 30 - 34
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0026068781
- ISSN
- 0105-1873
- DOI
- 10.1111/j.1600-0536.1991.tb01626.x
- language
- English
- LU publication?
- yes
- id
- 66fc0f06-9341-49c1-879a-8068bc015dca
- date added to LUP
- 2019-07-17 16:16:34
- date last changed
- 2022-08-12 02:38:55
@article{66fc0f06-9341-49c1-879a-8068bc015dca, abstract = {{Guinea pigs were sensitized to dinitrochlorobenzene (DNCB) by the intracutaneous route and challenged epicutaneously tin the flanks. The intensity of the allergic contact dermatitis was evaluated by inspection and palpation as well us by wet weight determination. With the purpose of diminishing tissue neuropeptides, and substance P in particular, the animals were treated with capsaicin either between induction and challenge, or before sensitization, In comparison with controls, the contact dermatitis was Enhanced in both groups of animals treated with capsaicin.}}, author = {{Wallengren, Joanna and Ekman, Rolf and Möller, Halvor}}, issn = {{0105-1873}}, language = {{eng}}, number = {{1}}, pages = {{30--34}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Capsaicin enhances allergic contact dermatitis in guinea pig.}}, url = {{http://dx.doi.org/10.1111/j.1600-0536.1991.tb01626.x}}, doi = {{10.1111/j.1600-0536.1991.tb01626.x}}, volume = {{24}}, year = {{1991}}, }