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Adipose tissue concentrations of dioxins and dibenzofurans in potentially exposed patients with malignant lymphoma or sarcoma

Hardell, L. ; Eriksson, M. LU orcid ; Athlin, L. ; Hansson, M. and Rappe, C. (1995) In Oncology Reports 2(5). p.749-753
Abstract

Epidemiological studies have suggested an association between exposure to phenoxyacetic acids, chlorophenols or their contaminating dioxins (PCDDs) and dibenzofurans (PCDFs) and soft-tissue sarcoma and malignant lymphoma. In this study adipose tissue concentrations of PCDDs and PCDFs were measured in nine patients with sarcoma or malignant lymphoma who had been exposed to phenoxyacetic acids or chlorophenols, or who had other potential exposure to dioxins and dibenzofurans. For comparison concentrations of PCDDs and PCDFs in a group of twelve healthy persons without any known exposure to the above chemicals and living in the same geographical area are presented. Even if no consistent pattern of PCDDs and PCDFs concentrations in the... (More)

Epidemiological studies have suggested an association between exposure to phenoxyacetic acids, chlorophenols or their contaminating dioxins (PCDDs) and dibenzofurans (PCDFs) and soft-tissue sarcoma and malignant lymphoma. In this study adipose tissue concentrations of PCDDs and PCDFs were measured in nine patients with sarcoma or malignant lymphoma who had been exposed to phenoxyacetic acids or chlorophenols, or who had other potential exposure to dioxins and dibenzofurans. For comparison concentrations of PCDDs and PCDFs in a group of twelve healthy persons without any known exposure to the above chemicals and living in the same geographical area are presented. Even if no consistent pattern of PCDDs and PCDFs concentrations in the patients was demonstrated, the finding of increased concentrations in all three cases with non-Hodgkin's lymphoma is of special interest. The exposure profiles in relation to measured concentrations of PCDDs and PCDFs are discussed for all patients.

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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Dibenzofurans, Dioxins, Malignant lymphoma, Soft-tissue sarcoma
in
Oncology Reports
volume
2
issue
5
pages
749 - 753
publisher
Spandidos Publications
external identifiers
  • scopus:0029114811
ISSN
1021-335X
language
English
LU publication?
no
id
6702a10f-c6e4-45fe-890b-54f692de5783
date added to LUP
2020-02-18 17:25:55
date last changed
2021-01-03 08:57:24
@article{6702a10f-c6e4-45fe-890b-54f692de5783,
  abstract     = {{<p>Epidemiological studies have suggested an association between exposure to phenoxyacetic acids, chlorophenols or their contaminating dioxins (PCDDs) and dibenzofurans (PCDFs) and soft-tissue sarcoma and malignant lymphoma. In this study adipose tissue concentrations of PCDDs and PCDFs were measured in nine patients with sarcoma or malignant lymphoma who had been exposed to phenoxyacetic acids or chlorophenols, or who had other potential exposure to dioxins and dibenzofurans. For comparison concentrations of PCDDs and PCDFs in a group of twelve healthy persons without any known exposure to the above chemicals and living in the same geographical area are presented. Even if no consistent pattern of PCDDs and PCDFs concentrations in the patients was demonstrated, the finding of increased concentrations in all three cases with non-Hodgkin's lymphoma is of special interest. The exposure profiles in relation to measured concentrations of PCDDs and PCDFs are discussed for all patients.</p>}},
  author       = {{Hardell, L. and Eriksson, M. and Athlin, L. and Hansson, M. and Rappe, C.}},
  issn         = {{1021-335X}},
  keywords     = {{Dibenzofurans; Dioxins; Malignant lymphoma; Soft-tissue sarcoma}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{5}},
  pages        = {{749--753}},
  publisher    = {{Spandidos Publications}},
  series       = {{Oncology Reports}},
  title        = {{Adipose tissue concentrations of dioxins and dibenzofurans in potentially exposed patients with malignant lymphoma or sarcoma}},
  volume       = {{2}},
  year         = {{1995}},
}